Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 2794106..2794624 Replicon chromosome
Accession NZ_CP076132
Organism Flammeovirga yaeyamensis strain NBRC:100898

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KMW28_RS11005 Protein ID WP_169663376.1
Coordinates 2794355..2794624 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag KMW28_RS11000 Protein ID WP_169663377.1
Coordinates 2794106..2794354 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KMW28_RS10980 (KMW28_10980) 2789366..2790625 - 1260 WP_169663381.1 T9SS type A sorting domain-containing protein -
KMW28_RS10985 (KMW28_10985) 2790861..2791577 + 717 WP_169663380.1 leucyl/phenylalanyl-tRNA--protein transferase -
KMW28_RS10990 (KMW28_10990) 2791626..2793080 + 1455 WP_169663379.1 aminoacyl-histidine dipeptidase -
KMW28_RS10995 (KMW28_10995) 2793545..2794054 - 510 WP_169663378.1 DUF255 domain-containing protein -
KMW28_RS11000 (KMW28_11000) 2794106..2794354 + 249 WP_169663377.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
KMW28_RS11005 (KMW28_11005) 2794355..2794624 + 270 WP_169663376.1 Txe/YoeB family addiction module toxin Toxin
KMW28_RS11010 (KMW28_11010) 2794687..2796825 + 2139 WP_169663375.1 DPP IV N-terminal domain-containing protein -
KMW28_RS11015 (KMW28_11015) 2797095..2798393 + 1299 WP_169663374.1 dicarboxylate/amino acid:cation symporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10860.60 Da        Isoelectric Point: 10.5642

>T204688 WP_169663376.1 NZ_CP076132:2794355-2794624 [Flammeovirga yaeyamensis]
MNILFSKTAWQQYLFWQTEDKKITLRIHELIKNIQRDPFKGIGKPEPLRQNLTGFWSRRINSEHRLIYRIVGKKNEGQRI
EIISCQYHY

Download         Length: 270 bp

>T204688 NZ_CP101210:c4326894-4326517 [Escherichia coli]
ATGAAAACATTATCCGACACACATGTACGGGAGGTATCTCGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGGTTGCTGGACCAGCACTACGGCCTCACGCTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCGCAGGAACTTCGTCGCAGTTAATCAACAGCATTGATATTCTCCGGGCACGCCGGGCAACAGGTCTGATGACCCGCAG
CAACTACAGAACGGTAAATAACATTACCCTGGGGAAGCATCCGGAGGCGAAACAATGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9490.73 Da        Isoelectric Point: 4.3142

>AT204688 WP_169663377.1 NZ_CP076132:2794106-2794354 [Flammeovirga yaeyamensis]
MNTTTLSDLRANLKSYFDELEDNKDILIVPRSGNKEAIVLMTLSEYNSMKETEYLLSSKNNRELLEKSIKELDGEDTIKF
EL

Download         Length: 249 bp

>AT204688 NZ_CP101210:c4327315-4326941 [Escherichia coli]
GTGTCAGACACACTCCCCGGGACAACGCTTCCCGACGACAATAACGACCGCACCTGGTGGGGACTGCCCTGCACCGTGAC
GCCCTGTTTTGGGGCACGTCTGGTACAGGAAGGCAACCGGTTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGGCGGT
TCAGCGACGCAGATGCATACCATCCGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGACATCAGCATACCGTCACGCTGTATGCAAAAGGGCTGACCTGCGAAGCCGACACCCTCGGCTCCTG
TGGTTACGTTTATCTGGCTGTTTATCCGACACCGGCACCCGCAATCACCTCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References