204623

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 2209435..2209979 Replicon chromosome
Accession NZ_CP076104
Organism Nocardioides sp. LMS-CY

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KM427_RS10720 Protein ID WP_183590440.1
Coordinates 2209698..2209979 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KM427_RS10715 Protein ID WP_183590441.1
Coordinates 2209435..2209701 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KM427_RS10695 (KM427_10695) 2206226..2206666 + 441 WP_215527166.1 SRPBCC family protein -
KM427_RS10700 (KM427_10700) 2206666..2207859 + 1194 WP_215527167.1 ArsA family ATPase -
KM427_RS10705 (KM427_10705) 2207861..2208250 + 390 WP_215527168.1 hypothetical protein -
KM427_RS10710 (KM427_10710) 2208441..2209382 + 942 WP_183590442.1 ROK family glucokinase -
KM427_RS10715 (KM427_10715) 2209435..2209701 + 267 WP_183590441.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
KM427_RS10720 (KM427_10720) 2209698..2209979 + 282 WP_183590440.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KM427_RS10725 (KM427_10725) 2210012..2210980 + 969 WP_183590439.1 ROK family protein -
KM427_RS10730 (KM427_10730) 2210913..2212157 - 1245 WP_183590438.1 TIGR00300 family protein -
KM427_RS10735 (KM427_10735) 2212195..2212686 - 492 WP_215527169.1 hypothetical protein -
KM427_RS10740 (KM427_10740) 2212708..2213481 - 774 WP_215527170.1 alpha/beta fold hydrolase -
KM427_RS10745 (KM427_10745) 2213597..2214322 + 726 WP_215527591.1 lysophospholipid acyltransferase family protein -
KM427_RS10750 (KM427_10750) 2214330..2214833 + 504 WP_215527171.1 flavin reductase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(36-90)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10332.95 Da        Isoelectric Point: 8.4934

>T204623 WP_183590440.1 NZ_CP076104:2209698-2209979 [Nocardioides sp. LMS-CY]
VSTSPPYELVLAPPAVRALQSGLPEPVATAVIEFLTGPLLENPQRVGKALRGELAGIRAARRGTYRVLYRIDDEADEILV
MRIEHRAEVYRPR

Download         Length: 282 bp

>T204623 NZ_CP101172:c4601221-4601069 [Xanthomonas campestris pv. campestris]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTCTCGGCCGGCATGATGACTGGCTGTAACACCATGGCTGGTGC
CGGAAAGGACATGCAGGGTGCGGGTGACAAGGTCGAGAAGACCGCCGACAAATGCAGCGACGGTAAGTGCTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9810.96 Da        Isoelectric Point: 4.7132

>AT204623 WP_183590441.1 NZ_CP076104:2209435-2209701 [Nocardioides sp. LMS-CY]
MSVEPLREVRNHFSDVIDRVEREHERVTVTRNGRAAAVIISPDDLAELEETLAVLSDPQAMADIREADAAYRTGDVVRGA
DAVRALRR

Download         Length: 267 bp

>AT204623 NZ_CP101172:c4600989-4600855 [Xanthomonas campestris pv. campestris]
ATGAAGCGTGCAATTGCATTGTTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCCGCGCGCAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References