Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 342921..343732 Replicon chromosome
Accession NZ_CP076104
Organism Nocardioides sp. LMS-CY

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag KM427_RS01605 Protein ID WP_215526028.1
Coordinates 343295..343732 (+) Length 146 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag KM427_RS01600 Protein ID WP_215526027.1
Coordinates 342921..343223 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KM427_RS01575 (KM427_01575) 339041..339943 - 903 WP_215526022.1 S-4TM family putative pore-forming effector -
KM427_RS01580 (KM427_01580) 339943..340794 - 852 WP_215526023.1 CBASS oligonucleotide cyclase -
KM427_RS01585 (KM427_01585) 340808..341317 - 510 WP_215526024.1 hypothetical protein -
KM427_RS01590 (KM427_01590) 341327..341809 - 483 WP_215526025.1 hypothetical protein -
KM427_RS01595 (KM427_01595) 341811..342707 - 897 WP_215526026.1 AAA family ATPase -
KM427_RS01600 (KM427_01600) 342921..343223 + 303 WP_215526027.1 DUF1778 domain-containing protein Antitoxin
KM427_RS01605 (KM427_01605) 343295..343732 + 438 WP_215526028.1 GNAT family N-acetyltransferase Toxin
KM427_RS01610 (KM427_01610) 343722..344888 - 1167 WP_215526029.1 hypothetical protein -
KM427_RS01615 (KM427_01615) 345494..348184 + 2691 WP_215526030.1 DEAD/DEAH box helicase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(28-117)

Antitoxin

Vibrio phage ICP1, Orf50

(16-91)


Sequences

Toxin        


Download         Length: 146 a.a.        Molecular weight: 15980.28 Da        Isoelectric Point: 6.9235

>T204620 WP_215526028.1 NZ_CP076104:343295-343732 [Nocardioides sp. LMS-CY]
MDDWLKRYSLINQHAGMATTFVTTVGDSGEVVGFYSLATGGVDHQDAPARVTRGVPKHPIPVIVLARLAVHEDHHGQKLG
RGLLRDALVRVSNAAEEIGVRALLLHAKDHEARDFYLAQAEFEPSPIDPLQLFLLLKDLRKSVSQ

Download         Length: 438 bp

>T204620 NZ_CP101170:c4512359-4512207 [Xanthomonas campestris pv. campestris]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTCTCGGCCGGCATGATGACTGGCTGTAACACCATGGCTGGTGC
CGGAAAGGACATGCAGGGTGCGGGTGACAAGGTCGAGAAGACCGCCGACAAATGCAGCGACGGTAAGTGCTAA

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11224.45 Da        Isoelectric Point: 4.8892

>AT204620 WP_215526027.1 NZ_CP076104:342921-343223 [Nocardioides sp. LMS-CY]
MPTEEAATARPARDSRLNIRTSAKQDNLIRQAAQAVDKSVSEFVLDSATATAEHVLADRRYFAVSDDAWQAFEAALERPA
VFKPRLHELLNEDSPFEPQR

Download         Length: 303 bp

>AT204620 NZ_CP101170:c4512130-4511996 [Xanthomonas campestris pv. campestris]
ATGAAGCGTGCAATTGCATTGTTGGTGCTGTCGATGTTGTCGGTTGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCCGCGCGCAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References