Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | TsaAT/- |
Location | 315795..316272 | Replicon | chromosome |
Accession | NZ_CP076029 | ||
Organism | Staphylococcus sp. MZ9 |
Toxin (Protein)
Gene name | TsaT | Uniprot ID | T1Y7S2 |
Locus tag | KI244_RS01525 | Protein ID | WP_000052076.1 |
Coordinates | 315795..315983 (-) | Length | 63 a.a. |
Antitoxin (Protein)
Gene name | TsaA | Uniprot ID | T1Y6P8 |
Locus tag | KI244_RS01530 | Protein ID | WP_001059690.1 |
Coordinates | 316012..316272 (-) | Length | 87 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
KI244_RS01495 (KI244_01495) | 311837..312307 | + | 471 | WP_000824472.1 | hypothetical protein | - |
KI244_RS01500 (KI244_01500) | 312648..313333 | + | 686 | Protein_283 | thermonuclease family protein | - |
KI244_RS01505 (KI244_01505) | 313690..313890 | + | 201 | WP_001059082.1 | cold-shock protein | - |
KI244_RS01510 (KI244_01510) | 314386..314604 | - | 219 | WP_000005886.1 | hypothetical protein | - |
KI244_RS01515 (KI244_01515) | 314666..314950 | - | 285 | WP_001004401.1 | hypothetical protein | - |
KI244_RS01520 (KI244_01520) | 315038..315607 | - | 570 | WP_045178121.1 | lipoprotein N-acylation protein LnsA | - |
KI244_RS01525 (KI244_01525) | 315795..315983 | - | 189 | WP_000052076.1 | hypothetical protein | Toxin |
KI244_RS01530 (KI244_01530) | 316012..316272 | - | 261 | WP_001059690.1 | hypothetical protein | Antitoxin |
KI244_RS01535 (KI244_01535) | 316613..316816 | + | 204 | WP_000145163.1 | sterile alpha motif-like domain-containing protein | - |
KI244_RS01540 (KI244_01540) | 316813..317049 | - | 237 | WP_000368687.1 | hypothetical protein | - |
KI244_RS01545 (KI244_01545) | 317274..317855 | + | 582 | WP_214958375.1 | histidine phosphatase family protein | - |
KI244_RS01550 (KI244_01550) | 317928..318545 | - | 618 | WP_000255553.1 | LysE/ArgO family amino acid transporter | - |
KI244_RS01555 (KI244_01555) | 318700..319194 | - | 495 | WP_000569884.1 | GNAT family N-acetyltransferase | - |
KI244_RS01560 (KI244_01560) | 319593..320015 | - | 423 | WP_000974460.1 | organic hydroperoxide resistance protein | - |
KI244_RS01565 (KI244_01565) | 320163..320879 | + | 717 | WP_000150017.1 | type I 3-dehydroquinate dehydratase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 63 a.a. Molecular weight: 7142.82 Da Isoelectric Point: 9.9971
>T204567 WP_000052076.1 NZ_CP076029:c315983-315795 [Staphylococcus sp. MZ9]
MSLHFAILFWLALIFLVAATFILVLMKKTGKESKKESYLSFTVILYIFGFAILIYTFIFGVL
MSLHFAILFWLALIFLVAATFILVLMKKTGKESKKESYLSFTVILYIFGFAILIYTFIFGVL
Download Length: 189 bp
>T204567 NZ_CP100765:4190831-4191175 [Serratia nematodiphila]
ATGTGGCAAGTGGTGACCGTCGAACGGTTTGACGACTGGTTTTTAGCGCTGAACAACGCCCAGCAAACAAGCATCCTGGC
GGCGATCTACAAATTGCAGACGTTCGGCCCGCAATTGGCGCGGCCGCATGCCGATACGCTGCATTTTTCCGACGCGGTCC
GACAGTTGAAGGAGCTGCGCATTCAACATCGCGGGTGCCCTTTCAGGGTGTTTTTCGCCTTTGATCCACAGCGGCAAGCG
GTATTGCTGTGCGGCGGCGATAAAACCGGCGACAAACGCTTTTACCAGCGCATGTTGCCCATCGCCGCCATGGAGTTTTC
ACATTATCTGGCAACCCGGAGGTAG
ATGTGGCAAGTGGTGACCGTCGAACGGTTTGACGACTGGTTTTTAGCGCTGAACAACGCCCAGCAAACAAGCATCCTGGC
GGCGATCTACAAATTGCAGACGTTCGGCCCGCAATTGGCGCGGCCGCATGCCGATACGCTGCATTTTTCCGACGCGGTCC
GACAGTTGAAGGAGCTGCGCATTCAACATCGCGGGTGCCCTTTCAGGGTGTTTTTCGCCTTTGATCCACAGCGGCAAGCG
GTATTGCTGTGCGGCGGCGATAAAACCGGCGACAAACGCTTTTACCAGCGCATGTTGCCCATCGCCGCCATGGAGTTTTC
ACATTATCTGGCAACCCGGAGGTAG
Antitoxin
Download Length: 87 a.a. Molecular weight: 9940.09 Da Isoelectric Point: 4.0624
>AT204567 WP_001059690.1 NZ_CP076029:c316272-316012 [Staphylococcus sp. MZ9]
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYSFIG
Download Length: 261 bp
>AT204567 NZ_CP100765:4191181-4191483 [Serratia nematodiphila]
ATGGCCAAACCTTTATCCCAACTGATCGATAAACTCGATCCCGCCGTCGTTGCCGCCGCCAGGCAAAAAGCGGACCAGGA
GATTTTCGAGCTGCGGCTGGCGATGCTGAGGGAAGAGTTGGCGGTTTCTCAGGTTGAATTGGCGAAGCGGCTCGGCATCA
GCCAACCCTCCGTCGCCAATTTGGAAAAGCGCGGCAGCGAAATCAAGCTGTCATCGCTCAAACGCTATATTGAGGCGATG
GGCGGCACGCTGTCGCTGGATGTGCAATTGCCCAATGGCCAGCACCGCCGCATGACGCTGTGA
ATGGCCAAACCTTTATCCCAACTGATCGATAAACTCGATCCCGCCGTCGTTGCCGCCGCCAGGCAAAAAGCGGACCAGGA
GATTTTCGAGCTGCGGCTGGCGATGCTGAGGGAAGAGTTGGCGGTTTCTCAGGTTGAATTGGCGAAGCGGCTCGGCATCA
GCCAACCCTCCGTCGCCAATTTGGAAAAGCGCGGCAGCGAAATCAAGCTGTCATCGCTCAAACGCTATATTGAGGCGATG
GGCGGCACGCTGTCGCTGGATGTGCAATTGCCCAATGGCCAGCACCGCCGCATGACGCTGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0E0VP18 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0E0VN56 |