Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) FaRel2-ATfaRel2/-
Location 26843..27638 Replicon plasmid pCPCPI53k-r1_1
Accession NZ_CP075935
Organism Clostridium perfringens strain CPI 53k-r1

Toxin (Protein)


Gene name faRel2 Uniprot ID -
Locus tag KLF52_RS15225 Protein ID WP_173706021.1
Coordinates 26843..27433 (+) Length 197 a.a.

Antitoxin (Protein)


Gene name ATfaRel2 Uniprot ID B1BRB4
Locus tag KLF52_RS15230 Protein ID WP_004456691.1
Coordinates 27414..27638 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KLF52_RS15170 (KLF52_15155) 22085..22297 + 213 WP_173706015.1 hypothetical protein -
KLF52_RS15175 (KLF52_15160) 22284..23243 + 960 WP_173706016.1 hypothetical protein -
KLF52_RS15180 (KLF52_15165) 23253..23525 + 273 WP_224390678.1 hypothetical protein -
KLF52_RS15185 (KLF52_15170) 23641..23901 + 261 WP_004456627.1 hypothetical protein -
KLF52_RS15190 (KLF52_15175) 24194..24547 + 354 WP_173706018.1 hypothetical protein -
KLF52_RS15195 (KLF52_15180) 24564..24953 + 390 WP_173706019.1 hypothetical protein -
KLF52_RS15200 (KLF52_15185) 24970..25290 + 321 WP_004456606.1 hypothetical protein -
KLF52_RS15205 (KLF52_15190) 25294..25680 + 387 WP_004456489.1 hypothetical protein -
KLF52_RS15210 (KLF52_15195) 25700..26122 + 423 WP_004456648.1 hypothetical protein -
KLF52_RS15215 (KLF52_15200) 26236..26466 + 231 WP_173706020.1 hypothetical protein -
KLF52_RS15220 (KLF52_15205) 26512..26823 + 312 WP_004456613.1 hypothetical protein -
KLF52_RS15225 (KLF52_15210) 26843..27433 + 591 WP_173706021.1 hypothetical protein Toxin
KLF52_RS15230 (KLF52_15215) 27414..27638 + 225 WP_004456691.1 hypothetical protein Antitoxin
KLF52_RS15235 (KLF52_15220) 27669..28619 - 951 WP_221366827.1 hypothetical protein -
KLF52_RS15240 (KLF52_15225) 28990..29520 + 531 WP_173706024.1 hypothetical protein -
KLF52_RS15245 (KLF52_15230) 29513..29908 + 396 WP_173706025.1 hypothetical protein -
KLF52_RS15250 (KLF52_15235) 29987..31111 + 1125 WP_173706026.1 nuclease-related domain-containing protein -
KLF52_RS15255 (KLF52_15240) 31244..31531 + 288 WP_043013024.1 hypothetical protein -
KLF52_RS15260 (KLF52_15245) 31655..31942 + 288 WP_004456644.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..129891 129891


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RelA/SpoT

(57-159)

Antitoxin

Protein of unknown function DUF6718

(1-72)


Sequences

Toxin        


Download         Length: 197 a.a.        Molecular weight: 23493.87 Da        Isoelectric Point: 9.2173

>T204496 WP_173706021.1 NZ_CP075935:26843-27433 [Clostridium perfringens]
MIDISILDKLSYKSNLNKSLKNTLRKFNKEDIMTELLDIRGFYEKNQLLTTIKFDYRIKSFQSSLLKYDKYFPSTELKKC
FNDLLGFRIVIDNYNELDNISLENFRIADMRNGKANDDGYRGIHLYYQKSNRHYPIELQINTVKDRIFNDWLHQELYKYV
SNNNIGIELRKKYDDGIITSLEDFKGELKKHVLYNI

Download         Length: 591 bp

>T204496 NZ_CP100739:c4273184-4272693 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATGATCTCCACCCCTGAGCCGCTTCATGCCGGACATATTCTTACTCCGTTTTGCTGCGGTGTGGATTCTATAGATAACTG
GCTGGAACAGCGGGCGATGAAAAATCAGACCACTGGCGCGTCCCGTACCTTTGTGTGTTGTGGCAGCGATTCGAACGTAC
TGGCCTATTACTCGCTGGCGTCCAGCGCGGTCACGACGAATACCTCCCCCGGTCGCTTTCGTCGCAATATGCCTGACCCG
ATTCCGGTTGTGGTATTGGGGCGTCTGGCGGTGGATAAATCGCTTCATGGGCAGGGCGTCGCTCGGGCGCTGGTACGCGA
CGCAGGGCTGCGGGTTATTCAGGTGGCGGAGACTATCGGCATTCGTGGGATGCTGGTTCACGCCCTGTCGGATGAAGCGC
GGGAATTTTATCAGCGGGTGGGGTTTGTACCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGGGGGATTTGGTG
GAGAGTGTTTAA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8547.92 Da        Isoelectric Point: 5.0178

>AT204496 WP_004456691.1 NZ_CP075935:27414-27638 [Clostridium perfringens]
MCYIISKKFNELGCYALKSELGDKLASLSRYLTLATLDKNVQIVTISDPNVYKEYEPYTFVISEKEFINKTLEL

Download         Length: 225 bp

>AT204496 NZ_CP100739:c4273474-4273181 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATGCCAGCCGCAAACAGTATGGCGATGAAACGCGAAACCCTGAACCTGCGTATCAAACCCGCCGAGCGCGATCTTATCGA
TCGAGCGGCGAAAGCCAGAGGGAAAAACCGCACAGACTTTGTGCTGGAAGCTGCCCGCGCTGCCGCAGAGGAAGCGCTTA
TCGAACAACGCATCATTATGGCCGATCCAGAGGCTTATCAGGAGTTTCTCGTTCGTTTGGATCAAACACCTTCACCTAAT
GCCGCACTGCGTAAAACCATGCAGACCCCTGCGCCGTGGGAGCAGGAAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References