Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yjhX-yjhQ/YjhX(toxin) |
Location | 5935361..5936180 | Replicon | chromosome |
Accession | NZ_CP075881 | ||
Organism | Klebsiella michiganensis strain JNQH491 |
Toxin (Protein)
Gene name | yjhX | Uniprot ID | J5WT09 |
Locus tag | KLH67_RS28030 | Protein ID | WP_004110819.1 |
Coordinates | 5935923..5936180 (-) | Length | 86 a.a. |
Antitoxin (Protein)
Gene name | yjhQ | Uniprot ID | - |
Locus tag | KLH67_RS28025 | Protein ID | WP_046877056.1 |
Coordinates | 5935361..5935912 (-) | Length | 184 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
KLH67_RS28010 (KLH67_28005) | 5931585..5932493 | - | 909 | WP_049104432.1 | transcriptional regulator GcvA | - |
KLH67_RS28015 (KLH67_28010) | 5932613..5933500 | + | 888 | WP_049084232.1 | DMT family transporter | - |
KLH67_RS31375 | 5933715..5934461 | - | 747 | WP_223226754.1 | class I SAM-dependent methyltransferase | - |
KLH67_RS31380 | 5934888..5935247 | - | 360 | Protein_5506 | class I SAM-dependent methyltransferase | - |
KLH67_RS28025 (KLH67_28020) | 5935361..5935912 | - | 552 | WP_046877056.1 | N-acetyltransferase | Antitoxin |
KLH67_RS28030 (KLH67_28025) | 5935923..5936180 | - | 258 | WP_004110819.1 | YjhX family toxin | Toxin |
KLH67_RS28035 (KLH67_28030) | 5936856..5938040 | + | 1185 | WP_014228054.1 | mannonate dehydratase | - |
KLH67_RS28040 (KLH67_28035) | 5938114..5939589 | + | 1476 | WP_014228053.1 | fructuronate reductase | - |
KLH67_RS28045 (KLH67_28040) | 5939729..5940505 | + | 777 | WP_004847986.1 | Uxu operon transcriptional regulator | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 86 a.a. Molecular weight: 9552.07 Da Isoelectric Point: 11.1381
>T204453 WP_004110819.1 NZ_CP075881:c5936180-5935923 [Klebsiella michiganensis]
MNLSRQEQRTLHVLAKGGRIAHIRDASGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR
MNLSRQEQRTLHVLAKGGRIAHIRDASGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR
Download Length: 258 bp
>T204453 NZ_CP100732:365062-365337 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATGGGGCAAAGGGAAATTGAATATTCGGGACAGTTCCAGAAAGATGTAAAACGGGCACAAAAGCGTCATAAGGATGTCGG
CAAACTTAAAACACTTATGACGCTTCTGATTCACCACCCTTTTCCCCTTCCTGCCATTTATAAAGATCACCCGTTACAAG
GTTCATATAGCGGATACCGGGATGCCCATATTGAGCCTGACTGGATTCTTATTTATAAGATAACGGATGAATGCCTGCGA
TTTGAACGAACAGGAACGCATGCCGATTTATTTTAA
ATGGGGCAAAGGGAAATTGAATATTCGGGACAGTTCCAGAAAGATGTAAAACGGGCACAAAAGCGTCATAAGGATGTCGG
CAAACTTAAAACACTTATGACGCTTCTGATTCACCACCCTTTTCCCCTTCCTGCCATTTATAAAGATCACCCGTTACAAG
GTTCATATAGCGGATACCGGGATGCCCATATTGAGCCTGACTGGATTCTTATTTATAAGATAACGGATGAATGCCTGCGA
TTTGAACGAACAGGAACGCATGCCGATTTATTTTAA
Antitoxin
Download Length: 184 a.a. Molecular weight: 19998.88 Da Isoelectric Point: 6.3992
>AT204453 WP_046877056.1 NZ_CP075881:c5935912-5935361 [Klebsiella michiganensis]
MTNHSFTFHVASEGDTDDILDVETRAFGYSKEARLVADLLNDESACPTLSLLARHNGEAVGHILFTRATFKGEPDSPMMH
ILAPLAVVPEYQGVGVGGGLIRHGIEQLKAMGSQMVFVLGHAAYYPRLGFEPCAGDKGYPAPYPIPEAHKACWMLQPLSS
QPLGRTGQIQCARALMKPEHWRE
MTNHSFTFHVASEGDTDDILDVETRAFGYSKEARLVADLLNDESACPTLSLLARHNGEAVGHILFTRATFKGEPDSPMMH
ILAPLAVVPEYQGVGVGGGLIRHGIEQLKAMGSQMVFVLGHAAYYPRLGFEPCAGDKGYPAPYPIPEAHKACWMLQPLSS
QPLGRTGQIQCARALMKPEHWRE
Download Length: 552 bp
>AT204453 NZ_CP100732:364799-365059 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATGGCTGCAAATGCGCTTGTTCGTGCCCGTATCGACGAAACGCTGAAGGACCAGGCGGCAGATGTCCTGGCTGAAATGGG
GTTAACCATTTCTGATTTGATACGGATTACACTGACTAAAGTTGCGCGTGAAAAGGCATTGCCTTTTGATTTGCGCATAC
CCAATGAGTTAACGTCCCGAACGATAGAAAATAGCGAAGCTGGCGTTGATATTCATAAAGCCAAAGATGCTGATGATTTG
TTTGACCAGTTAGGGATCTGA
ATGGCTGCAAATGCGCTTGTTCGTGCCCGTATCGACGAAACGCTGAAGGACCAGGCGGCAGATGTCCTGGCTGAAATGGG
GTTAACCATTTCTGATTTGATACGGATTACACTGACTAAAGTTGCGCGTGAAAAGGCATTGCCTTTTGATTTGCGCATAC
CCAATGAGTTAACGTCCCGAACGATAGAAAATAGCGAAGCTGGCGTTGATATTCATAAAGCCAAAGATGCTGATGATTTG
TTTGACCAGTTAGGGATCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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