Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3293906..3294071 Replicon chromosome
Accession NZ_CP075881
Organism Klebsiella michiganensis strain JNQH491

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3293964..3294067 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3293906..3294071 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KLH67_RS15470 (KLH67_15470) 3289033..3291093 + 2061 WP_033836507.1 oligopeptidase B -
KLH67_RS15475 (KLH67_15475) 3291100..3291759 - 660 WP_014229839.1 exodeoxyribonuclease X -
KLH67_RS15480 (KLH67_15480) 3291838..3292068 - 231 WP_004103351.1 DNA polymerase III subunit theta -
KLH67_RS15485 (KLH67_15485) 3292204..3292578 + 375 WP_014229838.1 CopC domain-containing protein YobA -
KLH67_RS15490 (KLH67_15490) 3292583..3293452 + 870 WP_049082451.1 copper homeostasis membrane protein CopD -
KLH67_RS15495 (KLH67_15495) 3293469..3293807 + 339 WP_004103344.1 YebY family protein -
- 3293906..3294071 - 166 - - Antitoxin
- 3293964..3294067 + 104 - - Toxin
KLH67_RS15500 (KLH67_15500) 3294145..3295230 - 1086 WP_154904340.1 tyrosine-type recombinase/integrase -
KLH67_RS15505 (KLH67_15505) 3295199..3295471 - 273 WP_131050309.1 excisionase -
KLH67_RS15510 (KLH67_15510) 3295555..3296184 - 630 WP_154904341.1 Eac protein -
KLH67_RS15515 (KLH67_15515) 3296242..3296598 - 357 WP_154904342.1 DUF2591 family protein -
KLH67_RS15520 (KLH67_15520) 3296873..3297094 - 222 WP_154904343.1 TraR/DksA family transcriptional regulator -
KLH67_RS15525 (KLH67_15525) 3297091..3297363 - 273 WP_154904344.1 hypothetical protein -
KLH67_RS15530 (KLH67_15530) 3297383..3297676 - 294 WP_154904345.1 sigma-70 family RNA polymerase sigma factor -
KLH67_RS15535 (KLH67_15535) 3297673..3298269 - 597 WP_154904346.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3267828..3367516 99688


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T204444 NZ_CP075881:3293964-3294067 [Klebsiella michiganensis]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTTTTTTT

Antitoxin


Download         Length: 166 bp

>AT204444 NZ_CP075881:c3294071-3293906 [Klebsiella michiganensis]
AGATAAAAAAAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTG
GCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGCGACAAAAGTGGAC
GAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References