Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 646818..647089 Replicon chromosome
Accession NZ_CP075665
Organism Escherichia coli strain STEC2018-553

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 646948..647051 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 646818..647089 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JFY30_RS03095 643373..644035 - 663 WP_000944256.1 exodeoxyribonuclease X -
JFY30_RS03100 644059..644715 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
JFY30_RS03105 644817..645047 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JFY30_RS03110 645186..645560 + 375 WP_000204699.1 CopC domain-containing protein YobA -
JFY30_RS03115 645564..646436 + 873 WP_000879285.1 copper homeostasis membrane protein CopD -
JFY30_RS03120 646449..646790 + 342 WP_000976492.1 YebY family protein -
- 646818..647089 - 272 - - Antitoxin
- 646948..647051 + 104 - - Toxin
JFY30_RS03125 647186..647842 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
JFY30_RS03130 647843..648034 - 192 WP_001296140.1 YebW family protein -
JFY30_RS03135 648139..648375 - 237 WP_001295499.1 YebV family protein -
JFY30_RS03140 648493..649932 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T204182 NZ_CP075665:646948-647051 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT204182 NZ_CP075665:c647089-646818 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References