Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4774217..4774488 Replicon chromosome
Accession NZ_CP075652
Organism Escherichia coli strain STEC17-183

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4774347..4774450 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4774217..4774488 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JFX43_RS23095 4770772..4771434 - 663 WP_000944256.1 exodeoxyribonuclease X -
JFX43_RS23100 4771458..4772114 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
JFX43_RS23105 4772216..4772446 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JFX43_RS23110 4772585..4772959 + 375 WP_000204699.1 CopC domain-containing protein YobA -
JFX43_RS23115 4772963..4773835 + 873 WP_000879285.1 copper homeostasis membrane protein CopD -
JFX43_RS23120 4773848..4774189 + 342 WP_000976492.1 YebY family protein -
- 4774217..4774488 - 272 - - Antitoxin
- 4774347..4774450 + 104 - - Toxin
JFX43_RS23125 4774585..4775241 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
JFX43_RS23130 4775242..4775433 - 192 WP_001296140.1 YebW family protein -
JFX43_RS23135 4775538..4775774 - 237 WP_001295499.1 YebV family protein -
JFX43_RS23140 4775892..4777331 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 4695064..4790327 95263


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T204135 NZ_CP075652:4774347-4774450 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT204135 NZ_CP075652:c4774488-4774217 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References