Detailed information of TA system TA203913

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/-
• Location: 3733118..3733586
• Replicon: chromosome
• Accession: NZ_CP075567
• Organism: Pseudomonas fitomaticsae strain FIT81

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: KJY40_RS16660
• Protein ID: WP_230737711.1
• Coordinates: 3733359..3733586 (+)
• Length: 76 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: KJY40_RS16655
• Protein ID: WP_230731259.1
• Coordinates: 3733118..3733312 (+)
• Length: 65 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KJY40_RS16635 (KJY40_16595)	3728746..3729714	-	969	WP_230731253.1	Gfo/Idh/MocA family oxidoreductase	-
KJY40_RS16640 (KJY40_16600)	3729724..3730611	-	888	WP_230731255.1	Dyp-type peroxidase	-
KJY40_RS16645 (KJY40_16605)	3730669..3731703	-	1035	WP_230731257.1	AraC family transcriptional regulator	-
KJY40_RS16650 (KJY40_16610)	3731915..3732862	+	948	WP_230731258.1	transporter	-
KJY40_RS16655 (KJY40_16615)	3733118..3733312	+	195	WP_230731259.1	stability determinant	Antitoxin
KJY40_RS16660 (KJY40_16620)	3733359..3733586	+	228	WP_230737711.1	type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family	Toxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• HipA, N-terminal subdomain 1 (5-103)

Antitoxin

• Cro/C1-type helix-turn-helix domain (16-65)

Sequences

Toxin

Protein

• Length: 76 a.a.
• Molecular weight: 8506.70 Da
• Isoelectric Point: 11.4092

>T203913 WP_230737711.1 NZ_CP075567:3733359-3733586 [Pseudomonas fitomaticsae]
IEQYNSNASTALQHKVGAATQRLSSIPYGYRSGRVPGTREMVVNPNYLLVYRVNGRIKILTLVHTRRQYPRTSST

Nucleotide

• Length: 228 bp

>T203913 NZ_CP100478:c2611394-2610072 [Klebsiella pneumoniae]
ATGGCGACGCTTACCACCTGGATGAACAATGTGCGCGTGGGAACCTTAACCCGCCAGGCTAACGGGGCGCACAGTTTTCG
CTATGACGAAGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCCCTCTCACTGCCGCTGCAGTATGGCAATATCACTG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGACCGGATCGTCAGGCGCTATCAG
GCGCGCTCGAAGCAGCCGTTCGATCTGCTGGCCGAAGTCGGGCGGGATAGCGTAGGGGCGGTGACCCTCCTGCCGCCGGG
GGAAGAGGCGCACCTGGAAGGATTACGCTGGCAGACGCTGGACGAGGCGCAGCTCACCGCTTTGCTGACCGCTTACCAGT
CGGATATCCCCCTCGGGATGATTACCAGCCAGGACGATTTCCGTATCTCGGTGGCCGGCGCCCAGGAGAAAACGGCGCTG
CTGCGGATGGGCGAGCAGTGGTGTATTCCGCAGGGCGCCACGCCGACCACGCATATCATTAAGCTGCCCATCGGCGAGAT
CAAGCAGCCCAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAATGAGTATCTGTGCCTGGCGCTGGCCAGAGAACTGG
GCCTGGCGGTGCCGGAAGCGGAGATCATCACCACCCCGCGGATCCGCGCCCTGGCGGTAACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGACGGGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCTTTTGGTCTTCCTTCAGCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGCTCGAGTGAAGCGCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTCTTCCAGTGGCTGACGGGGGCGACGGACGGTCACGCAAAAAACTTCTCAATTTACCTGTTG
CCCGGCGGCAGCTACCGCTTAACACCGTTCTACGACATTATTTCGGCGTTTCCGGTGCTGGGCGGCACGGGACTGCATCT
GCGCGATCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGTAAAACAGAGATTAACGCCATCTATCCGCGTCATT
TTCTGGCGACGGCCAAAGCGGTGAACTTTCCCCTGGAGCAGATGCTGGCGATCCTCCAGGAGTTTGCCGGGCATGTGCCG
CAGGCAATCGAAAGCGCTCGCCGGACGCTGCCGGCGGACTTTTCCAGCCACGTCTGGCAGGCCATTACAGAGAACATGCT
GAAGCTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGCTATAG

Antitoxin

Protein

• Length: 65 a.a.
• Molecular weight: 7597.41 Da
• Isoelectric Point: 4.4791

>AT203913 WP_230731259.1 NZ_CP075567:3733118-3733312 [Pseudomonas fitomaticsae]
MSILHSPFYSDFDSEEEAESYDRWFRAKVQEALDDPSPGIPHEEAMMRLDQLLEERRKNRRAVA

Nucleotide

• Length: 195 bp

>AT203913 NZ_CP100478:c2611660-2611394 [Klebsiella pneumoniae]
ATGAATTCCCCGCAGATATACAGTCCCGTGCAGCTGGCCAATTACCTGAAGCTGCTGCGCCAGCAGAACCACTGGACCCA
GGATGCGCTGGCCAGGCGGATCGGCATTAAGCAGGCCACGCTGTCCAATTTTGAAAATCACCCCGACAAAACCACCTTAA
CCACGCTGTTTAAGATCCTCCAGTCGCTGGGGGTGGTGATGACGCTGAACGCCAAAGCTGCTGAGACGGCGCCGGCTCCC
GATAACAACACGGACCTTGACTGGTAA