Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 6402607..6403203 Replicon chromosome
Accession NZ_CP075566
Organism Pseudomonas fluorescens strain G20-18

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KJF94_RS29650 Protein ID WP_214380464.1
Coordinates 6402901..6403203 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KJF94_RS29645 Protein ID WP_214380463.1
Coordinates 6402607..6402897 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KJF94_RS29625 (KJF94_29625) 6398761..6400878 - 2118 WP_214380459.1 TonB-dependent copper receptor -
KJF94_RS29630 (KJF94_29630) 6401101..6401559 - 459 WP_214380460.1 DUF2946 domain-containing protein -
KJF94_RS29635 (KJF94_29635) 6401581..6402060 - 480 WP_214380461.1 copper chaperone PCu(A)C -
KJF94_RS29640 (KJF94_29640) 6402109..6402507 - 399 WP_214380462.1 DUF2946 domain-containing protein -
KJF94_RS29645 (KJF94_29645) 6402607..6402897 - 291 WP_214380463.1 putative addiction module antidote protein Antitoxin
KJF94_RS29650 (KJF94_29650) 6402901..6403203 - 303 WP_214380464.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KJF94_RS29655 (KJF94_29655) 6403394..6404122 - 729 WP_214380465.1 cobalt-precorrin-6A reductase -
KJF94_RS29660 (KJF94_29660) 6404119..6405216 - 1098 WP_214380466.1 cobalt-precorrin-5B (C(1))-methyltransferase -
KJF94_RS29665 (KJF94_29665) 6405209..6406420 - 1212 WP_214380467.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -
KJF94_RS29670 (KJF94_29670) 6406588..6407340 + 753 WP_214380468.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Uncharacterized protein HI1420

(4-95)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11436.97 Da        Isoelectric Point: 7.2768

>T203909 WP_214380464.1 NZ_CP075566:c6403203-6402901 [Pseudomonas fluorescens]
MIDFERSSAFADWLDSMRDTIGKARIIARLRAAEHGNFGDCEPVGESVYEMRVHHGPGYRMYFTRRGEVVYLLLVGGDKS
TQKRDIKRAIQMAQNIGNEE

Download         Length: 303 bp

>T203909 NZ_CP100478:324424-324792 [Klebsiella pneumoniae]
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCGGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTAATAAGCGTACGGCACTGTTT
ATCACCCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCAGCGAATCCAGACTTCGTCGGCATGACCGTCGAGGCAGC
AGCAGGGCAACTTACCCTGGAACAGATTGTCGCGCGTTTGCGTGGATGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10370.85 Da        Isoelectric Point: 4.5994

>AT203909 WP_214380463.1 NZ_CP075566:c6402897-6402607 [Pseudomonas fluorescens]
MAEQFTRFDAAEFLKSPEEMAAYLDACFEEDAGDGVLIRAALNDIARAQGMTQVARDAGLGRESLYKALSSTGNPEFATI
MKVMKALGLRLHATAI

Download         Length: 291 bp

>AT203909 NZ_CP100478:324206-324427 [Klebsiella pneumoniae]
ATGAGAACGGTTAACTATAGCGAAGCCCGGCAAAATCTGGCCGATGTGCTGGAAAGCGCAGTGACAGGTGTACCTGTGAC
CATTACCCGTCGTGGGCATAAATCTGCAGTCATCATTAGTGCAGAAGAGTTTGAACGCTACCAGGCGGCCAGAATGGATG
ATGAGTTCGCGGCTATCATGGCGGTTCATGGTGATGAGATCAGGGAGCTTGCGGATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References