Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1830918..1831063 Replicon chromosome
Accession NZ_CP075552
Organism Klebsiella pneumoniae strain RGF99-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1830954..1831056 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1830918..1831063 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KI681_RS08850 (KI681_08845) 1826048..1828108 + 2061 WP_048289976.1 oligopeptidase B -
KI681_RS08855 (KI681_08850) 1828112..1828771 - 660 WP_002911407.1 exodeoxyribonuclease X -
KI681_RS08860 (KI681_08855) 1828850..1829080 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KI681_RS08865 (KI681_08860) 1829193..1829567 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KI681_RS08870 (KI681_08865) 1829571..1830440 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
KI681_RS08875 (KI681_08870) 1830457..1830795 + 339 WP_016529031.1 YebY family protein -
- 1830918..1831063 - 146 - - Antitoxin
- 1830954..1831056 + 103 - - Toxin
KI681_RS08880 (KI681_08875) 1831430..1831573 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KI681_RS08885 (KI681_08880) 1831678..1832646 - 969 WP_004151446.1 VirK/YbjX family protein -
KI681_RS08890 (KI681_08885) 1832803..1833456 + 654 WP_020802220.1 protein-serine/threonine phosphatase -
KI681_RS08895 (KI681_08890) 1833453..1833644 - 192 WP_002911395.1 YebW family protein -
KI681_RS08900 (KI681_08895) 1833742..1833981 - 240 WP_002911393.1 YebV family protein -
KI681_RS08905 (KI681_08900) 1834097..1835530 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T203852 NZ_CP075552:1830954-1831056 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT203852 NZ_CP075552:c1831063-1830918 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References