Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1879222..1879367 Replicon chromosome
Accession NZ_CP075548
Organism Klebsiella pneumoniae strain RGT40-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1879258..1879360 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1879222..1879367 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KI675_RS09095 1874352..1876412 + 2061 WP_004151449.1 oligopeptidase B -
KI675_RS09100 1876416..1877075 - 660 WP_002911407.1 exodeoxyribonuclease X -
KI675_RS09105 1877154..1877384 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KI675_RS09110 1877497..1877871 + 375 WP_048279882.1 CopC domain-containing protein YobA -
KI675_RS09115 1877875..1878744 + 870 WP_004891049.1 copper homeostasis membrane protein CopD -
KI675_RS09120 1878761..1879099 + 339 WP_002911404.1 YebY family protein -
- 1879222..1879367 - 146 - - Antitoxin
- 1879258..1879360 + 103 - - Toxin
KI675_RS09125 1879736..1879879 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KI675_RS09130 1879984..1880952 - 969 WP_004151446.1 VirK/YbjX family protein -
KI675_RS09135 1881109..1881762 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
KI675_RS09140 1881759..1881950 - 192 WP_002911395.1 YebW family protein -
KI675_RS09145 1882048..1882287 - 240 WP_002911393.1 YebV family protein -
KI675_RS09150 1882403..1883836 - 1434 WP_065811950.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T203828 NZ_CP075548:1879258-1879360 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT203828 NZ_CP075548:c1879367-1879222 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References