Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1967729..1968000 Replicon chromosome
Accession NZ_CP075487
Organism Escherichia coli strain NT1F34

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1967859..1967962 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1967729..1968000 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IGI26_RS10040 1964284..1964946 - 663 WP_000944256.1 exodeoxyribonuclease X -
IGI26_RS10045 1964970..1965626 - 657 WP_000011660.1 carbon-nitrogen hydrolase family protein YobB -
IGI26_RS10050 1965728..1965958 - 231 WP_000916763.1 DNA polymerase III subunit theta -
IGI26_RS10055 1966097..1966471 + 375 WP_000255065.1 CopC domain-containing protein YobA -
IGI26_RS10060 1966475..1967347 + 873 WP_000879298.1 copper homeostasis membrane protein CopD -
IGI26_RS10065 1967360..1967701 + 342 WP_000976472.1 YebY family protein -
- 1967729..1968000 - 272 - - Antitoxin
- 1967859..1967962 + 104 - - Toxin
IGI26_RS10070 1968097..1968753 + 657 WP_000812733.1 protein-serine/threonine phosphatase -
IGI26_RS10075 1968754..1968945 - 192 WP_001313035.1 YebW family protein -
IGI26_RS10080 1969050..1969286 - 237 WP_001295499.1 YebV family protein -
IGI26_RS10085 1969404..1970843 - 1440 WP_024176540.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1943033..1983838 40805


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T203806 NZ_CP075487:1967859-1967962 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT203806 NZ_CP075487:c1968000-1967729 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References