Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2067255..2067526 Replicon chromosome
Accession NZ_CP075477
Organism Escherichia coli strain NT1W25

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2067385..2067488 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2067255..2067526 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IGI33_RS09930 2063810..2064472 - 663 WP_000944256.1 exodeoxyribonuclease X -
IGI33_RS09935 2064496..2065152 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
IGI33_RS09940 2065254..2065484 - 231 WP_000916763.1 DNA polymerase III subunit theta -
IGI33_RS09945 2065623..2065997 + 375 WP_000204699.1 CopC domain-containing protein YobA -
IGI33_RS09950 2066001..2066873 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
IGI33_RS09955 2066886..2067227 + 342 WP_000976472.1 YebY family protein -
- 2067255..2067526 - 272 - - Antitoxin
- 2067385..2067488 + 104 - - Toxin
IGI33_RS09960 2067623..2068279 + 657 WP_000812710.1 protein-serine/threonine phosphatase -
IGI33_RS09965 2068280..2068471 - 192 WP_001296140.1 YebW family protein -
IGI33_RS09970 2068576..2068812 - 237 WP_001295499.1 YebV family protein -
IGI33_RS09975 2068930..2070369 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T203723 NZ_CP075477:2067385-2067488 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT203723 NZ_CP075477:c2067526-2067255 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References