Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2525034..2525305 Replicon chromosome
Accession NC_002695
Organism Escherichia coli O157:H7 str. Sakai

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2525072..2525175 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2525034..2525305 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ECs_2545 2522110..2523630 + 1521 NP_310572.3 16S rRNA m(5)C1407 methyltransferase -
ECs_2546 2523748..2523984 + 237 NP_310573.2 hypothetical protein -
ECs_2547 2524005..2524280 + 276 NP_310574.1 hypothetical protein -
ECs_2548 2524281..2524937 - 657 NP_310575.2 serine/threonine-specific protein phosphatase 1 -
- 2525034..2525305 + 272 - - Antitoxin
- 2525072..2525175 - 104 - - Toxin
ECs_2549 2525333..2525674 - 342 NP_310576.1 hypothetical protein -
ECs_2550 2525687..2526559 - 873 NP_310577.1 inner membrane protein -
ECs_2551 2526563..2526937 - 375 NP_310578.1 hypothetical protein -
ECs_2552 2527076..2527306 + 231 NP_310579.1 DNA polymerase III theta subunit HolE -
ECs_2553 2527408..2528064 + 657 NP_310580.1 hypothetical protein -
ECs_2554 2528088..2528750 + 663 NP_310581.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T20356 NC_002695:c2525175-2525072 [Escherichia coli O157:H7 str. Sakai]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT20356 NC_002695:2525034-2525305 [Escherichia coli O157:H7 str. Sakai]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References