Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 2626601..2627234 Replicon chromosome
Accession NZ_CP075325
Organism Xanthomonas citri pv. citri strain GD82

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag KJA71_RS11620 Protein ID WP_015463212.1
Coordinates 2626601..2627014 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID M4TWF0
Locus tag KJA71_RS11625 Protein ID WP_015463213.1
Coordinates 2627001..2627234 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KJA71_RS11605 (KJA71_11605) 2622365..2624473 + 2109 WP_191105149.1 TonB-dependent siderophore receptor -
KJA71_RS11610 (KJA71_11610) 2624682..2626196 + 1515 WP_015463210.1 conjugal transfer protein TraG N-terminal domain-containing protein -
KJA71_RS11615 (KJA71_11615) 2626212..2626574 - 363 WP_015463211.1 DUF3742 family protein -
KJA71_RS11620 (KJA71_11620) 2626601..2627014 - 414 WP_015463212.1 PIN domain-containing protein Toxin
KJA71_RS11625 (KJA71_11625) 2627001..2627234 - 234 WP_015463213.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
KJA71_RS11630 (KJA71_11630) 2627516..2628523 + 1008 WP_223293118.1 DUF4917 family protein -
KJA71_RS11635 (KJA71_11635) 2628656..2629111 - 456 WP_015463215.1 hypothetical protein -
KJA71_RS11640 (KJA71_11640) 2629506..2630081 + 576 WP_011051400.1 sigma-70 family RNA polymerase sigma factor -
KJA71_RS11645 (KJA71_11645) 2630062..2631111 + 1050 WP_011051401.1 FecR domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-119)

Antitoxin

SpoVT-AbrB domain

(5-45)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15221.65 Da        Isoelectric Point: 6.3225

>T203455 WP_015463212.1 NZ_CP075325:c2627014-2626601 [Xanthomonas citri pv. citri]
MAAGKGKVFLDSNVVLYLLSEDAVKADGAEALLQRRPVISVQVLNEVTHVCVRKLKMGWDEVGQFLALVRSFCKIVPLTV
DVHDRARQLAERHQLSFYDACIVAAAAIEGCQTLYSEDMHHGLIIEESLSIRNPFNV

Download         Length: 414 bp

>T203455 NZ_CP100094:2024675-2024777 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8663.97 Da        Isoelectric Point: 8.7848

>AT203455 WP_015463213.1 NZ_CP075325:c2627234-2627001 [Xanthomonas citri pv. citri]
MQVAKWGNSLAVRLPSSLVEALELREGDDIEIVVDDPRLFAVRKKPGPEAMLERLRAFRGKLPADFKFNRDEANGRG

Download         Length: 234 bp

>AT203455 NZ_CP100094:c2024784-2024639 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB M4TWF0

References