Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 2020050..2020714 Replicon chromosome
Accession NZ_CP075325
Organism Xanthomonas citri pv. citri strain GD82

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag KJA71_RS09100 Protein ID WP_217377116.1
Coordinates 2020424..2020714 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag KJA71_RS09095 Protein ID WP_217377115.1
Coordinates 2020050..2020391 (-) Length 114 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KJA71_RS09040 (KJA71_09040) 2015156..2015662 + 507 WP_109291864.1 hypothetical protein -
KJA71_RS09045 (KJA71_09045) 2015659..2016279 + 621 WP_109291862.1 hypothetical protein -
KJA71_RS09050 (KJA71_09050) 2016276..2016650 + 375 WP_109291934.1 hypothetical protein -
KJA71_RS09055 (KJA71_09055) 2016647..2017360 + 714 WP_109291860.1 phage antirepressor KilAC domain-containing protein -
KJA71_RS09060 (KJA71_09060) 2017368..2017589 + 222 WP_217377110.1 hypothetical protein -
KJA71_RS09065 (KJA71_09065) 2017586..2017783 + 198 WP_217377111.1 hypothetical protein -
KJA71_RS09070 (KJA71_09070) 2017783..2017962 + 180 WP_104567163.1 hypothetical protein -
KJA71_RS09075 (KJA71_09075) 2017965..2018414 + 450 WP_209262166.1 hypothetical protein -
KJA71_RS09080 (KJA71_09080) 2018755..2019126 + 372 WP_217377112.1 Ref family recombination enhancement nuclease -
KJA71_RS09085 (KJA71_09085) 2019123..2019497 + 375 WP_217377113.1 hypothetical protein -
KJA71_RS09090 (KJA71_09090) 2019587..2019796 - 210 WP_217377114.1 hypothetical protein -
KJA71_RS09095 (KJA71_09095) 2020050..2020391 - 342 WP_217377115.1 putative addiction module antidote protein Antitoxin
KJA71_RS09100 (KJA71_09100) 2020424..2020714 - 291 WP_217377116.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KJA71_RS09105 (KJA71_09105) 2020806..2021306 + 501 WP_217377117.1 hypothetical protein -
KJA71_RS09110 (KJA71_09110) 2021303..2021617 + 315 WP_223293168.1 hypothetical protein -
KJA71_RS09115 (KJA71_09115) 2021614..2021931 + 318 WP_217377118.1 hypothetical protein -
KJA71_RS09120 (KJA71_09120) 2021918..2022331 + 414 WP_217377119.1 hypothetical protein -
KJA71_RS09125 (KJA71_09125) 2022341..2022487 + 147 WP_217377120.1 hypothetical protein -
KJA71_RS09130 (KJA71_09130) 2022484..2022759 + 276 WP_217377121.1 lipoprotein -
KJA71_RS09135 (KJA71_09135) 2022772..2024112 + 1341 WP_223293169.1 SGNH/GDSL hydrolase family protein -
KJA71_RS09140 (KJA71_09140) 2024130..2024423 + 294 WP_217377122.1 hypothetical protein -
KJA71_RS09145 (KJA71_09145) 2024426..2024590 + 165 WP_217377123.1 hypothetical protein -
KJA71_RS09150 (KJA71_09150) 2024587..2024793 + 207 WP_217377124.1 hypothetical protein -
KJA71_RS09155 (KJA71_09155) 2024790..2024957 + 168 WP_217377125.1 hypothetical protein -
KJA71_RS09160 (KJA71_09160) 2024957..2025388 + 432 WP_217377126.1 HNH endonuclease signature motif containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1995899..2047198 51299


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-89)

Antitoxin

Uncharacterized protein HI1420

(6-92)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10630.36 Da        Isoelectric Point: 10.1771

>T203454 WP_217377116.1 NZ_CP075325:c2020714-2020424 [Xanthomonas citri pv. citri]
MTTITATEEFTTWLRKLRDTKAKAVIIERVQRVARGLLGDVEPVGGPVSELRIHYGPGYRVYFTRRGEEVVILLCGGDKT
TQTKDIKKAQALAAGL

Download         Length: 291 bp

>T203454 NZ_CP100094:845683-846093 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGACGGATCCATGCCCGTCGCGGGGAAATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAGATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA

Antitoxin


Download         Length: 114 a.a.        Molecular weight: 12050.47 Da        Isoelectric Point: 4.3952

>AT203454 WP_217377115.1 NZ_CP075325:c2020391-2020050 [Xanthomonas citri pv. citri]
MTKTTTTPFDPAEYLDDDEAMATYLSEALDSGDTDHFQDALQVVARARGMAQIAEAAGLGRESLYKALKPGANPRFDTIQ
RVLTALGVRLSIGPAETVEATETAKAAYTVRAA

Download         Length: 342 bp

>AT203454 NZ_CP100094:845436-845702 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References