203431

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2162454..2162599 Replicon chromosome
Accession NZ_CP075316
Organism Klebsiella pneumoniae strain DD521

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2162490..2162592 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2162454..2162599 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KJA60_RS10420 2157584..2159644 + 2061 WP_004151449.1 oligopeptidase B -
KJA60_RS10425 2159648..2160307 - 660 WP_020324964.1 exodeoxyribonuclease X -
KJA60_RS10430 2160386..2160616 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KJA60_RS10435 2160729..2161103 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KJA60_RS10440 2161107..2161976 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
KJA60_RS10445 2161993..2162331 + 339 WP_002911404.1 YebY family protein -
- 2162454..2162599 - 146 - - Antitoxin
- 2162490..2162592 + 103 - - Toxin
KJA60_RS10450 2162968..2163111 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KJA60_RS10455 2163216..2164184 - 969 WP_004151446.1 VirK/YbjX family protein -
KJA60_RS10460 2164341..2164994 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
KJA60_RS10465 2164991..2165182 - 192 WP_002911395.1 YebW family protein -
KJA60_RS10470 2165280..2165519 - 240 WP_002911393.1 YebV family protein -
KJA60_RS10475 2165635..2167068 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2155000..2179996 24996


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T203431 NZ_CP075316:2162490-2162592 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT203431 NZ_CP075316:c2162599-2162454 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References