Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1960869..1961013 | Replicon | chromosome |
| Accession | NZ_CP075286 | ||
| Organism | Klebsiella pneumoniae strain YTF44-1 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1960905..1961007 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1960869..1961013 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KI725_RS09720 (KI725_09720) | 1955999..1958059 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| KI725_RS09725 (KI725_09725) | 1958063..1958722 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| KI725_RS09730 (KI725_09730) | 1958801..1959031 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| KI725_RS09735 (KI725_09735) | 1959144..1959518 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| KI725_RS09740 (KI725_09740) | 1959522..1960391 | + | 870 | WP_020956678.1 | copper homeostasis membrane protein CopD | - |
| KI725_RS09745 (KI725_09745) | 1960408..1960746 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 1960869..1961013 | - | 145 | - | - | Antitoxin |
| - | 1960905..1961007 | + | 103 | - | - | Toxin |
| KI725_RS09750 (KI725_09750) | 1961140..1961421 | - | 282 | Protein_1897 | tyrosine-type recombinase/integrase | - |
| KI725_RS09755 (KI725_09755) | 1961498..1961977 | + | 480 | WP_032419797.1 | lysis protein | - |
| KI725_RS28510 | 1962432..1962627 | + | 196 | Protein_1899 | DNA polymerase V | - |
| KI725_RS09760 (KI725_09760) | 1962766..1964271 | + | 1506 | WP_020956680.1 | hypothetical protein | - |
| KI725_RS09765 (KI725_09765) | 1964521..1964949 | - | 429 | WP_032419788.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| KI725_RS09770 (KI725_09770) | 1964959..1965240 | - | 282 | WP_032419786.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T203409 NZ_CP075286:1960905-1961007 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 145 bp
>AT203409 NZ_CP075286:c1961013-1960869 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT