Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1960869..1961013 Replicon chromosome
Accession NZ_CP075286
Organism Klebsiella pneumoniae strain YTF44-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1960905..1961007 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1960869..1961013 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KI725_RS09720 (KI725_09720) 1955999..1958059 + 2061 WP_004151449.1 oligopeptidase B -
KI725_RS09725 (KI725_09725) 1958063..1958722 - 660 WP_002911407.1 exodeoxyribonuclease X -
KI725_RS09730 (KI725_09730) 1958801..1959031 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KI725_RS09735 (KI725_09735) 1959144..1959518 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KI725_RS09740 (KI725_09740) 1959522..1960391 + 870 WP_020956678.1 copper homeostasis membrane protein CopD -
KI725_RS09745 (KI725_09745) 1960408..1960746 + 339 WP_002911404.1 YebY family protein -
- 1960869..1961013 - 145 - - Antitoxin
- 1960905..1961007 + 103 - - Toxin
KI725_RS09750 (KI725_09750) 1961140..1961421 - 282 Protein_1897 tyrosine-type recombinase/integrase -
KI725_RS09755 (KI725_09755) 1961498..1961977 + 480 WP_032419797.1 lysis protein -
KI725_RS28510 1962432..1962627 + 196 Protein_1899 DNA polymerase V -
KI725_RS09760 (KI725_09760) 1962766..1964271 + 1506 WP_020956680.1 hypothetical protein -
KI725_RS09765 (KI725_09765) 1964521..1964949 - 429 WP_032419788.1 type II toxin-antitoxin system PemK/MazF family toxin -
KI725_RS09770 (KI725_09770) 1964959..1965240 - 282 WP_032419786.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T203409 NZ_CP075286:1960905-1961007 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT203409 NZ_CP075286:c1961013-1960869 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References