Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3482202..3482347 Replicon chromosome
Accession NZ_CP075256
Organism Klebsiella pneumoniae strain SZP4-9-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3482209..3482311 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3482202..3482347 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KI741_RS16940 3477733..3479166 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
KI741_RS16945 3479282..3479521 + 240 WP_002911393.1 YebV family protein -
KI741_RS16950 3479619..3479810 + 192 WP_002911395.1 YebW family protein -
KI741_RS16955 3479807..3480460 - 654 WP_024622748.1 protein-serine/threonine phosphatase -
KI741_RS16960 3480617..3481585 + 969 WP_014907334.1 VirK/YbjX family protein -
KI741_RS16965 3481690..3481833 + 144 WP_038431282.1 Ecr family regulatory small membrane protein -
- 3482202..3482347 + 146 - - Antitoxin
- 3482209..3482311 - 103 - - Toxin
KI741_RS16970 3482470..3482808 - 339 WP_002911404.1 YebY family protein -
KI741_RS16975 3482825..3483694 - 870 WP_004175431.1 copper homeostasis membrane protein CopD -
KI741_RS16980 3483698..3484072 - 375 WP_039819395.1 CopC domain-containing protein YobA -
KI741_RS16985 3484185..3484415 + 231 WP_002911406.1 DNA polymerase III subunit theta -
KI741_RS16990 3484494..3485153 + 660 WP_002911407.1 exodeoxyribonuclease X -
KI741_RS16995 3485157..3487217 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T203389 NZ_CP075256:c3482311-3482209 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT203389 NZ_CP075256:3482202-3482347 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References