Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 2475742..2476349 Replicon chromosome
Accession NZ_CP075192
Organism Ferribacterium limneticum strain 132

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KI608_RS11800 Protein ID WP_226446475.1
Coordinates 2476053..2476349 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KI608_RS11795 Protein ID WP_226446473.1
Coordinates 2475742..2476047 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KI608_RS11780 (KI608_11780) 2473843..2474316 + 474 WP_226446468.1 nucleoside deaminase -
KI608_RS11785 (KI608_11785) 2474333..2474650 + 318 WP_226446470.1 hypothetical protein -
KI608_RS11790 (KI608_11790) 2474680..2475612 - 933 WP_226446471.1 toll/interleukin-1 receptor domain-containing protein -
KI608_RS11795 (KI608_11795) 2475742..2476047 - 306 WP_226446473.1 putative addiction module antidote protein Antitoxin
KI608_RS11800 (KI608_11800) 2476053..2476349 - 297 WP_226446475.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KI608_RS11805 (KI608_11805) 2476425..2477429 - 1005 WP_226446476.1 hypothetical protein -
KI608_RS11810 (KI608_11810) 2477522..2477905 - 384 WP_226446478.1 hypothetical protein -
KI608_RS11815 (KI608_11815) 2477964..2479154 + 1191 WP_226446480.1 succinyldiaminopimelate transaminase -
KI608_RS11820 (KI608_11820) 2479171..2479989 + 819 WP_226446482.1 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase -
KI608_RS11825 (KI608_11825) 2480017..2481204 + 1188 WP_226446484.1 PilT/PilU family type 4a pilus ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Cro/C1-type helix-turn-helix domain

(50-94)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11073.00 Da        Isoelectric Point: 10.5628

>T203380 WP_226446475.1 NZ_CP075192:c2476349-2476053 [Ferribacterium limneticum]
MYSIKTLPEFTEWLSALKYKSTLIRLVRRLDKVQRGNLGDVKAVGHGVFEMREHFGPGWRMYYVQRGAFLIVMLGGGEKS
TQAADLARAVKLAATIKE

Download         Length: 297 bp

>T203380 NZ_CP075192:c2476349-2476053 [Ferribacterium limneticum]
ATGTATTCGATCAAAACCCTGCCTGAATTTACCGAGTGGCTAAGCGCTCTGAAGTACAAGTCGACGCTGATCCGCTTGGT
CCGTCGGTTGGACAAGGTTCAGCGTGGCAATCTTGGCGATGTGAAGGCGGTCGGTCATGGCGTATTCGAGATGCGTGAGC
ATTTCGGGCCGGGCTGGCGGATGTATTACGTGCAGCGCGGAGCGTTTTTGATTGTGATGCTGGGCGGTGGCGAAAAATCG
ACGCAGGCCGCCGATCTAGCCCGAGCCGTGAAGTTGGCGGCGACGATCAAGGAGTGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10775.37 Da        Isoelectric Point: 5.1051

>AT203380 WP_226446473.1 NZ_CP075192:c2476047-2475742 [Ferribacterium limneticum]
MTKKIDPVGLPEFDLAEYLDSEVAISEYLNQTIADGDMAELAHALGVAARARGMTEVAKASGITREALYKALRPNASPRF
ETVSKVCAALGVRLVAQPINS

Download         Length: 306 bp

>AT203380 NZ_CP075192:c2476047-2475742 [Ferribacterium limneticum]
ATGACCAAGAAAATTGACCCTGTGGGTCTGCCCGAATTTGATCTGGCCGAATATCTGGACAGCGAAGTGGCGATTTCGGA
GTACCTGAACCAGACTATTGCCGATGGCGACATGGCTGAGCTCGCCCACGCCCTGGGTGTGGCGGCGCGCGCTCGTGGCA
TGACCGAGGTGGCCAAGGCTTCCGGTATCACCCGGGAGGCGCTCTACAAGGCGCTGCGCCCGAATGCCAGCCCGCGTTTT
GAAACCGTCAGCAAGGTTTGTGCGGCACTCGGTGTTCGTCTGGTGGCGCAGCCGATCAATTCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References