Detailed information of TA system TA203379

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-dinJ/YafQ-RelB
• Location: 1642609..1643140
• Replicon: chromosome
• Accession: NZ_CP075192
• Organism: Ferribacterium limneticum strain 132

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: KI608_RS07780
• Protein ID: WP_226451434.1
• Coordinates: 1642859..1643140 (+)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: dinJ
• Uniprot ID: -
• Locus tag: KI608_RS07775
• Protein ID: WP_226451433.1
• Coordinates: 1642609..1642872 (+)
• Length: 88 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KI608_RS07755 (KI608_07750)	1638135..1639061	+	927	WP_226451430.1	histone deacetylase family protein	-
KI608_RS07760 (KI608_07755)	1639173..1640393	+	1221	WP_226451431.1	aspartate kinase	-
KI608_RS07770 (KI608_07765)	1640677..1642116	-	1440	WP_226451432.1	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	-
KI608_RS07775 (KI608_07770)	1642609..1642872	+	264	WP_226451433.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
KI608_RS07780 (KI608_07775)	1642859..1643140	+	282	WP_226451434.1	type II toxin-antitoxin system YafQ family toxin	Toxin
KI608_RS07785 (KI608_07780)	1643255..1643560	-	306	WP_226451435.1	HigA family addiction module antitoxin	-
KI608_RS07790 (KI608_07785)	1643570..1643848	-	279	WP_226451436.1	type II toxin-antitoxin system RelE/ParE family toxin	-
KI608_RS07795 (KI608_07790)	1643940..1644176	-	237	WP_226451437.1	DUF2442 domain-containing protein	-
KI608_RS07805 (KI608_07800)	1644430..1644735	-	306	WP_226451438.1	type II toxin-antitoxin system RelE/ParE family toxin	-
KI608_RS07810 (KI608_07805)	1644735..1645007	-	273	WP_226451439.1	type II toxin-antitoxin system ParD family antitoxin	-
KI608_RS07815 (KI608_07810)	1645266..1646546	-	1281	WP_226451440.1	nucleotide sugar dehydrogenase	-
KI608_RS07820 (KI608_07815)	1646849..1647589	-	741	WP_226451441.1	WecB/TagA/CpsF family glycosyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (2-91)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-83)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10786.21 Da
• Isoelectric Point: 7.0621

>T203379 WP_226451434.1 NZ_CP075192:1642859-1643140 [Ferribacterium limneticum]
MRKIDPTGQFRRDYKREAKGQHRATLDAELEPVLEALASDQPLEPRHRDHALTGEWKDHRDCHVKPDLVLIYRKPDDVTL
QLVRLGSHSELGL

Nucleotide

• Length: 282 bp

>T203379 NZ_CP099975:2326816-2327112 [Halomonas sp. Y3]
ATGATCGAGCTTATCAAAACCGATGTCTTTGATCGGTGGCTGCGCAGCCTTCGTGACACTCGTGCCCGCGCCAAGATCAC
GGTGCGGCTCAGACGGCTCAGCCTCGGCAACCCCGGCGATGTCAAACCTGTCGGTGAAGGCATCTCGGAACTGCGCATAC
CCCATGGCCCCGGCTACCGGGTCTATTACCTCACCCGAGGCCCCATCGTAGTGGTCCTACTCTGCGGGGGCGACAAGGGC
AGCCAGCCCAGCGACATCGAGCAAGCCAAAGCCATTGCCAAGCAATGGAAGGAGTAA

Antitoxin

Protein

• Length: 88 a.a.
• Molecular weight: 9424.85 Da
• Isoelectric Point: 5.0893

>AT203379 WP_226451433.1 NZ_CP075192:1642609-1642872 [Ferribacterium limneticum]
MASNAVVRARIDEHIKEEASTVLAAMGLTVSDAFRIMLTRVAREKALPFEPLIPNETTIAAMREARAGNLKSFDSVGALM
ADLHAED

Nucleotide

• Length: 264 bp

>AT203379 NZ_CP099975:2327116-2327430 [Halomonas sp. Y3]
ATGGCAACCCAACAACAGGTGACATTCAGCCACTACGACACCGCCGAGTACCTCCAGACCGAAGAGGAGATCGCCGCCTA
CCTGGAAGCCGTGATGGAAGAGAATGATCCCTCACTCCTCGCTGCCGCTCTGGGTGACGTTGCCCGTGCACGCAACATGA
GCCAGCTGGCCAAAGAGGTCGGCATGAGCCGTGAGGGGCTTTACAAGGCGCTTTCAGGTGAAGGTAATCCCGCCTTCTCA
ACCATCAACAAGGTCGCCAATGCCCTGGGGCTACAGCTGACCATCAAGCCGATGTCCCCGCCTCCGGCCCCTTGA