Detailed information of TA system TA203378

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii-AbiEi
• Location: 1009926..1011448
• Replicon: chromosome
• Accession: NZ_CP075192
• Organism: Ferribacterium limneticum strain 132

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: -
• Locus tag: KI608_RS04875
• Protein ID: WP_226450899.1
• Coordinates: 1009926..1010825 (-)
• Length: 300 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: -
• Locus tag: KI608_RS04880
• Protein ID: WP_226450900.1
• Coordinates: 1010822..1011448 (-)
• Length: 209 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KI608_RS04850 (KI608_04850)	1005017..1005784	-	768	WP_226450894.1	hypothetical protein	-
KI608_RS04855 (KI608_04855)	1005765..1007459	-	1695	WP_226450895.1	GspE/PulE family protein	-
KI608_RS04860 (KI608_04860)	1007469..1008653	-	1185	WP_226450896.1	type II secretion system F family protein	-
KI608_RS04865 (KI608_04865)	1008665..1009099	-	435	WP_226450897.1	type II secretion system major pseudopilin GspG	-
KI608_RS04870 (KI608_04870)	1009212..1009841	+	630	WP_226450898.1	transglycosylase SLT domain-containing protein	-
KI608_RS04875 (KI608_04875)	1009926..1010825	-	900	WP_226450899.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
KI608_RS04880 (KI608_04880)	1010822..1011448	-	627	WP_226450900.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	Antitoxin
KI608_RS04885 (KI608_04885)	1011560..1012855	-	1296	WP_226450901.1	hemolysin family protein	-
KI608_RS04890 (KI608_04890)	1013342..1014391	+	1050	WP_226446022.1	IS630 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (35-256)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (15-62)

Sequences

Toxin

Protein

• Length: 300 a.a.
• Molecular weight: 32578.79 Da
• Isoelectric Point: 7.4184

>T203378 WP_226450899.1 NZ_CP075192:c1010825-1009926 [Ferribacterium limneticum]
MKKDLATSVRARLLNTAKAQGADFNQILVRFALERILYRLSQSAYADHFLLKGALLFTLWYDMPHRSTRDADLLGFGASD
LESIARTFHDIASIEVADGIVFDPASVSVEEIRKDAGYAGARVLITAEIAKARCKTQIDIGFGDAVTPGPVHAAYPVLID
DLPAPQLRTNPVYTVIAEKLHAIALLGMTNSRLKDYLDIWVLLDREVLNANTLAKAIAATFIRRGMPLPVVLPVGLTDEF
ATDTSRQAMWQAFLKKNEIVMAPLPEVVAKLRTTLAPILIQAASIQATGGSDKSLQSAP

Nucleotide

• Length: 900 bp

>T203378 NZ_CP099975:1985534-1985716 [Halomonas sp. Y3]
GTGAAAAGCAGCGAGCTGATCAAGGAGCTGGAGGCCGCTGGCTGGGTACTGGACCGAATACGGGGCAGCCACCACGTCTT
CAAGCACCCCGAGAGGTCTGGTGCTATCCCCGTTCCACACCCGAAAAAGGACTTGCCCAGGGGTACTGTCCACCAGATTC
GGAAGCAAGCGGGACTCGCATAA

Antitoxin

Protein

• Length: 209 a.a.
• Molecular weight: 23618.55 Da
• Isoelectric Point: 9.8379

>AT203378 WP_226450900.1 NZ_CP075192:c1011448-1010822 [Ferribacterium limneticum]
MEQTWPIMSPNTHTQRVLDLARQKGTLRSRDLDEIGAPRVILTRLTTTGLLEKTGRGIYRLPDSQVSEHENLLAIATKVP
QAVFCLLTALQFHELTTQLPRRIWIAMPRGSHTPKINYPPLKMVQFAGDSYAEGIEVVERDQVKLRIYCVAKTIADCFKH
RNKIGLDVALEALKDAKAQKKASADELWRFAKICRVANVMRPYLEALE

Nucleotide

• Length: 627 bp

>AT203378 NZ_CP099975:1985735-1986139 [Halomonas sp. Y3]
ATGCAATATCCCATCGCTATCGAGTGGGGAGACGATAACACCGCTACCGGCATCGTCTTTCCTGATATTCCCGGCGCTAT
CAGTGCCGGGGACAGCCCTGAGGAGGCATACGACAACGCGGTAGAGGCCGCGCAGATCGTTCTCCAGGAGCTGGTGAGCC
GTGGCGAATCCGTCCCAAAGCCGGGGAAGATCAACGAACATCGCCGCAACCCCGACTTCGAGGGCTGGGGCTGGGGCATG
ATCGACATCGACCTGACGCCGTATCTTGGGAAGACAGAAAAAGTGACGGTCACGCTGCCCGGCATCGTGGTCCGTCAAAT
CGACGAGTACGTGACCCTGCACGGCATCAAGAGTCGGTCAGCGTTCTTGAGTAACGCGGCCCTGGAGAAGTTGCAGCATG
TCTAG