203376

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 88723..90449 Replicon chromosome
Accession NZ_CP075192
Organism Ferribacterium limneticum strain 132

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag KI608_RS00395 Protein ID WP_226449611.1
Coordinates 88723..89367 (+) Length 215 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag KI608_RS00400 Protein ID WP_226449613.1
Coordinates 89367..90449 (+) Length 361 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KI608_RS20310 (KI608_00380) 84137..85282 + 1146 WP_264180038.1 class I SAM-dependent DNA methyltransferase -
KI608_RS20315 (KI608_00385) 85230..86909 + 1680 WP_264180039.1 SAM-dependent methyltransferase -
KI608_RS00385 (KI608_00390) 86902..88149 + 1248 WP_226449607.1 restriction endonuclease subunit S -
KI608_RS00390 (KI608_00395) 88154..88726 + 573 WP_226449609.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
KI608_RS00395 (KI608_00400) 88723..89367 + 645 WP_226449611.1 DUF4433 domain-containing protein Toxin
KI608_RS00400 (KI608_00405) 89367..90449 + 1083 WP_226449613.1 macro domain-containing protein Antitoxin
KI608_RS00405 (KI608_00410) 90458..93718 + 3261 WP_226449615.1 HsdR family type I site-specific deoxyribonuclease -
KI608_RS00410 (KI608_00415) 93718..94425 + 708 WP_226449617.1 SprT family zinc-dependent metalloprotease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(14-214)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 215 a.a.        Molecular weight: 24644.22 Da        Isoelectric Point: 7.9511

>T203376 WP_226449611.1 NZ_CP075192:88723-89367 [Ferribacterium limneticum]
MIYKNLNPEKALIWRIVHRDNLPWILDNGLHCRNSQFQDPNFVNIGNPELIDKRAHRGVPITPGGTLSDYVPFYFTPFSV
MMKNIHSGWGGIRQRSNAEIVILVSSLRRVQEQGIPFLFTNGHAYPPDTRFFNDLSDLSVIDWGILQKRDFKRDLDDPKK
LERYQAEALIHQHLPVSGLVGAVCYTEAIKSDIEQQILARGLSLQVVARTEWYF

Download         Length: 645 bp

>T203376 NZ_CP099975:1924862-1925161 [Halomonas sp. Y3]
ATGCTCGATATTAAACAAACAGACACGTACCGAAAATGGGAGCGTAAGCTGCGAGATCAACGCGCCAAGGCGCTGATTGC
AGCGCGTGTTTTCCGCCTCGCCAATGGCTTGCCAGGGGATGTCCAGCCTGTAGGGCAGGGCGTCAGCGAGCTACGCATTC
ATCATGGTCCTGGCTATCGTATCTATTTCAAACAGCGCGGCAGCGAAATTGTCATCCTTCTGTGTGGTGGCGACAAGAGT
ACGCAGCAGCGCGATATCGAGACAGCACAGCGTCTTGCAGCAGAGTGGGAGGCCTTATGA

Antitoxin


Download         Length: 361 a.a.        Molecular weight: 40541.90 Da        Isoelectric Point: 6.8696

>AT203376 WP_226449613.1 NZ_CP075192:89367-90449 [Ferribacterium limneticum]
MIRFTQGNLLESQAEALVNTVNTVGVMGKGIALMFKERFSANFLAYAAACKAKQVQTGKMFVTEVHELGGPRWIVNFPTK
RHWKAPSELVWVKDGLQDLRRFLLEKKVKSIAIPPLGAGNGGLEWPEVREQIKLALEDLDVEILVFEPTSQYQNVAKRSG
TEKLTPARALIAELVRRYWVLGMECSLLEIQKLAWFMERAIERFSLENNPLKLEFKAHIYGPFTPKLNFVLDNLDGSYLH
CDKRISDASPLDVIWFDDSRKDLVQAYLKTEARQYSEALEYVGELIDGFESPFGMELLATVDWLLTRENAEPTVTGIRQA
LGAWPAGAAAAARKLRLFDERSVGFALERLTKAQPVPLAA

Download         Length: 1083 bp

>AT203376 NZ_CP099975:1925158-1925454 [Halomonas sp. Y3]
ATGAGCGACAAGATTTTTGACTACGACCCGGCAGCCGCCCTGGAAAGCGAGGAAGCGATTGCGGTATTTCTGGCGGATGC
CCTGGAAACAGGAGACTCCGCCTACATTGCCAAGGCGATGGGTGTAGTAGCACGCGCCAAAGGCATGAGCGAGCTCGCCC
GGGAAACCGGACTTTCCCGTGAGCAGCTGTATCGCTCTTTCAGTGAGCAGGGGAATCCCACGCTGAAAACCATGCTGGCC
GTGATGCGAGCCCTTGGCGTTGACTTGACGGCTCGCCCGCACGAGCCGGCTGCTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References