Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 2475740..2476347 Replicon chromosome
Accession NZ_CP075191
Organism Ferribacterium limneticum strain 128

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KI617_RS11800 Protein ID WP_226446475.1
Coordinates 2476051..2476347 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KI617_RS11795 Protein ID WP_226446473.1
Coordinates 2475740..2476045 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KI617_RS11780 (KI617_11780) 2473841..2474314 + 474 WP_226446468.1 nucleoside deaminase -
KI617_RS11785 (KI617_11785) 2474331..2474648 + 318 WP_226446470.1 hypothetical protein -
KI617_RS11790 (KI617_11790) 2474678..2475610 - 933 WP_226446471.1 toll/interleukin-1 receptor domain-containing protein -
KI617_RS11795 (KI617_11795) 2475740..2476045 - 306 WP_226446473.1 putative addiction module antidote protein Antitoxin
KI617_RS11800 (KI617_11800) 2476051..2476347 - 297 WP_226446475.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KI617_RS11805 (KI617_11805) 2476423..2477427 - 1005 WP_226446476.1 hypothetical protein -
KI617_RS11810 (KI617_11810) 2477520..2477903 - 384 WP_226446478.1 hypothetical protein -
KI617_RS11815 (KI617_11815) 2477962..2479152 + 1191 WP_226446480.1 succinyldiaminopimelate transaminase -
KI617_RS11820 (KI617_11820) 2479169..2479987 + 819 WP_226446482.1 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase -
KI617_RS11825 (KI617_11825) 2480015..2481202 + 1188 WP_226446484.1 PilT/PilU family type 4a pilus ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Cro/C1-type helix-turn-helix domain

(50-94)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11073.00 Da        Isoelectric Point: 10.5628

>T203373 WP_226446475.1 NZ_CP075191:c2476347-2476051 [Ferribacterium limneticum]
MYSIKTLPEFTEWLSALKYKSTLIRLVRRLDKVQRGNLGDVKAVGHGVFEMREHFGPGWRMYYVQRGAFLIVMLGGGEKS
TQAADLARAVKLAATIKE

Download         Length: 297 bp

>T203373 NZ_CP099975:c1208493-1208239 [Halomonas sp. Y3]
ATGGAAGCCATCAGCTACACAGCCGCACGCAGTCAACTGGCCCAGACCATGCAGCAGGTCTGTGACGACCATGCGCCGCT
GATCATTACCCGCAGCAAGGCGCCTTCGGTGGTGATGATCTCGCTGGAGGACTACGAGGCCCTTCAGGAAACCGCCTACC
TGCTGCGCTCGCCGAAGAACGCCCGGCGTCTTCTTGAATCCATTGCACAGCTCGAGGAAAGGGGCGGTCTAGAGCGGGAG
CTTATCGAGGAATGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10775.37 Da        Isoelectric Point: 5.1051

>AT203373 WP_226446473.1 NZ_CP075191:c2476045-2475740 [Ferribacterium limneticum]
MTKKIDPVGLPEFDLAEYLDSEVAISEYLNQTIADGDMAELAHALGVAARARGMTEVAKASGITREALYKALRPNASPRF
ETVSKVCAALGVRLVAQPINS

Download         Length: 306 bp

>AT203373 NZ_CP099975:c1208242-1207988 [Halomonas sp. Y3]
ATGAAGCTGACGTTCTCGGAGCACGCCTGGGAGGAGTATCTCTACTGGCAAAAGGCAGACAAGAAGGTGCTGCGCCGAAT
CAACCAGCTGATCAAGGAGATTCAGCGCACTCCCTTCGAGGGCATCGGCAAGCCTGAACCCCTGAAACACGGCCTTGCCG
GCTACTGGTCCCGGCGCATCAACGATGAACACCGGCTCGTCTACACGATCAACGAGGATGCCGTGCTGATCGCTCAGCTG
CGCTATCACTACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References