203368

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 3188071..3188500 Replicon chromosome
Accession NZ_CP075190
Organism Ferribacterium limneticum strain 76

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KI613_RS15265 Protein ID WP_226400933.1
Coordinates 3188071..3188337 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag KI613_RS15270 Protein ID WP_226400935.1
Coordinates 3188330..3188500 (-) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KI613_RS15250 (KI613_15170) 3183338..3184552 - 1215 WP_226400927.1 CaiB/BaiF CoA-transferase family protein -
KI613_RS15255 (KI613_15175) 3184552..3185337 - 786 WP_226400929.1 glutamate racemase -
KI613_RS15260 (KI613_15180) 3185823..3187877 - 2055 WP_226400931.1 diguanylate cyclase -
KI613_RS15265 (KI613_15185) 3188071..3188337 - 267 WP_226400933.1 Txe/YoeB family addiction module toxin Toxin
KI613_RS15270 (KI613_15190) 3188330..3188500 - 171 WP_226400935.1 hypothetical protein Antitoxin
KI613_RS15275 (KI613_15195) 3188645..3189904 - 1260 WP_226400937.1 HD-GYP domain-containing protein -
KI613_RS15280 (KI613_15200) 3189989..3190480 - 492 WP_226400939.1 RNA methyltransferase -
KI613_RS15285 (KI613_15205) 3190489..3190992 - 504 WP_226400941.1 hypothetical protein -
KI613_RS15290 (KI613_15210) 3191043..3191615 - 573 WP_226400942.1 hypothetical protein -
KI613_RS15295 (KI613_15215) 3191898..3192221 + 324 WP_226400944.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(4-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10322.63 Da        Isoelectric Point: 5.0622

>T203368 WP_226400933.1 NZ_CP075190:c3188337-3188071 [Ferribacterium limneticum]
MPSQITWTLAAWEENQCWQGQDSKTLKRINAVIRDCLREPFDGIGKPEPLKENLSGFWYRRIDDTNRLVYCVDGGNQVII
ACRYHYDD

Download         Length: 267 bp

>T203368 NZ_CP099973:c4180008-4179517 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGATCTCCACCCCTGAGCCGCTTCATGCCGGACATATTCTTACTCCGTTTTGCTGCGGTGTGGATTCTATAGATAACTG
GCTGAAACAGCGGGCGATGAAAAATCAGACCACTGGCGCGTCCCGTACCTTTGTGTGTTGTGGCAGCGATTCGAACGTAC
TGGCCTATTACTCGCTGGCGTCCAGCGCGGTCACGACGAATACCTCCCCCGGTCGCTTTCGTCGCAATATGCCTGACCCG
ATTCCGGTTGTGGTATTGGGGCGTCTGGCGGTGGATAAATCGCTTCATGGGCAGGGCGTCGCTCGGGCGCTGGTACGCGA
CGCAGGGCTGCGGGTTATTCAGGTGGCGGAGACTATCGGCATTCGTGGGATGCTGGTTCACGCCCTGTCGGATGAAGCGC
GGGAATTTTATCAGCGGGTGGGGTTTGTACCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGGGGGATTTGGTG
GAGAGTGTTTAA

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6211.09 Da        Isoelectric Point: 5.6863

>AT203368 WP_226400935.1 NZ_CP075190:c3188500-3188330 [Ferribacterium limneticum]
MRVVNFSDAVVMSLDTFNSLMETVQLLKSPANAAHLVRSIEQYRKGKTEAQDLADA

Download         Length: 171 bp

>AT203368 NZ_CP099973:c4180298-4180005 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGCCAGCCGCAAACAGTATGGCGATGAAACGCGAAACCCTGAACCTGCGTATCAAACCCGCCGAGCGCGATCTTATTGA
TCGAGCGGCGAAAGCCAGAGGGAAAAACCGCACTGACTTTGTGCTGGAAGCTGCCCGTGCTGCCGCCGAGGAAGCGCTGA
TCGAACAACGCATCATTATGGCCGATCCAGAGGCTTATCAGGAGTTTCTCGTTCGTTTGGATCAAACACCTTCACCTAAT
GCCGCACTGCGTAAAACCATGCAGACCCCTGCGCCGTGGGAGCAGGAAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References