Detailed information of TA system TA203364

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PumAB/upstrm_HI1419-dnstrm_HI1420
• Location: 2989193..2989800
• Replicon: chromosome
• Accession: NZ_CP075188
• Organism: Quatrionicoccus australiensis strain D9

Toxin (Protein)

• Gene name: PumA
• Uniprot ID: -
• Locus tag: KI612_RS14290
• Protein ID: WP_226440739.1
• Coordinates: 2989501..2989800 (-)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: PumB
• Uniprot ID: -
• Locus tag: KI612_RS14285
• Protein ID: WP_226440738.1
• Coordinates: 2989193..2989504 (-)
• Length: 104 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KI612_RS14260 (KI612_14315)	2985642..2985809	+	168	WP_226440733.1	DNA-binding protein	-
KI612_RS14265 (KI612_14320)	2985806..2986321	+	516	WP_226440734.1	hypothetical protein	-
KI612_RS14270 (KI612_14325)	2986415..2987524	-	1110	WP_226440735.1	hypothetical protein	-
KI612_RS14275 (KI612_14330)	2987664..2988467	-	804	WP_226440736.1	Sir2 family NAD-dependent protein deacetylase	-
KI612_RS14280 (KI612_14335)	2988912..2989088	+	177	WP_226440737.1	hypothetical protein	-
KI612_RS14285 (KI612_14340)	2989193..2989504	-	312	WP_226440738.1	putative addiction module antidote protein	Antitoxin
KI612_RS14290 (KI612_14345)	2989501..2989800	-	300	WP_226440739.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Addiction module killer protein, predicted (3-97)

Antitoxin

• Uncharacterized protein HI1420 (4-94)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11280.04 Da
• Isoelectric Point: 10.1713

>T203364 WP_226440739.1 NZ_CP075188:c2989800-2989501 [Quatrionicoccus australiensis]
MIEIIQSETFARWLGKLKDRSAVMRINARLRRLTETGNFGDVKPVREGVSEMRIDYGPGYRLYFVQNGPVLVVLLAGGDK
NTQDADIKRAIDISKEWKP

Nucleotide

• Length: 300 bp

>T203364 NZ_CP099973:3602470-3602727 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGAATGCCTCCGGCGTCAGCGTCCGCCACATCAACAGCAAAACCCACATGACCACCTATTACTCACAAATCCCCAGCCT
GCATCTTAAGGGCGACTGGCTGGAAGAAGCGGGATTTAAGACCGGGCGCGGCGTCACCGTGAAGATTTCACAGGGGTGTA
TTGTGCTGATGGCGGACAGTAACGAGGAGCAGAAGCTGCGCGAGCAGCTTTATCAGGCTAAACAGGTGGTTAAGGGAATT
AAGGACGTGCTGGTTTAG

Antitoxin

Protein

• Length: 104 a.a.
• Molecular weight: 11069.59 Da
• Isoelectric Point: 4.7921

>AT203364 WP_226440738.1 NZ_CP075188:c2989504-2989193 [Quatrionicoccus australiensis]
MTEKFTRWDPVDQLLSGEDMALYLDACLDEDNGDGSVVRAALNDIARAQGMSQLARDTGLTREGLYKALSPAGNPEFSTI
LKVIKALKIKLHATPGGDHLVAA

Nucleotide

• Length: 312 bp

>AT203364 NZ_CP099973:c3602645-3602313 [Salmonella enterica subsp. enterica serovar Enteritidis]
TCCGCCATCAGCACAATACACCCCTGTGAAATCTTCACGGTGACGCCGCGCCCGGTCTTAAATCCCGCTTCTTCCAGCCA
GTCGCCCTTAAGATGCAGGCTGGGGATTTGTGAGTAATAGGTGGTCATGTGGGTTTTGCTGTTGATGTGGCGGACGCTGA
CGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTAATTATCCGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTG
AGCGAGTATGGGCGCGACATCCTGGCACTGAGCCCCCCTCTCCCCGGCCAGCTCCGGGCGGTGATGAGCAACCGGCTGCC
GGGGCCGTATTTT