Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 3010421..3011024 Replicon chromosome
Accession NZ_CP075183
Organism Hydrogenophaga taeniospiralis strain LT2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KI616_RS14790 Protein ID WP_226462153.1
Coordinates 3010421..3010738 (-) Length 106 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KI616_RS14795 Protein ID WP_226462154.1
Coordinates 3010773..3011024 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KI616_RS14770 (KI616_14730) 3005742..3006008 - 267 WP_226462152.1 DUF4212 domain-containing protein -
KI616_RS14775 (KI616_14735) 3006396..3006704 + 309 WP_177139738.1 DUF485 domain-containing protein -
KI616_RS14780 (KI616_14740) 3006704..3008428 + 1725 WP_226467053.1 cation acetate symporter -
KI616_RS14785 (KI616_14745) 3010279..3010431 + 153 Protein_2920 IS1595 family transposase -
KI616_RS14790 (KI616_14750) 3010421..3010738 - 318 WP_226462153.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KI616_RS14795 (KI616_14755) 3010773..3011024 - 252 WP_226462154.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
KI616_RS14800 (KI616_14760) 3011362..3011595 - 234 WP_226462155.1 DUF6471 domain-containing protein -
KI616_RS14805 (KI616_14765) 3011727..3011975 + 249 WP_226462156.1 hypothetical protein -
KI616_RS14810 (KI616_14770) 3012438..3012743 - 306 WP_226462157.1 hypothetical protein -
KI616_RS14815 (KI616_14775) 3013014..3013694 + 681 WP_264186232.1 IS1595 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-76)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-77)


Sequences

Toxin        


Download         Length: 106 a.a.        Molecular weight: 11573.48 Da        Isoelectric Point: 9.8345

>T203359 WP_226462153.1 NZ_CP075183:c3010738-3010421 [Hydrogenophaga taeniospiralis]
MPEALEEWRNLDGSVQANLKKLLAKRLDNPRVPGGELHGPLAGCYKIKLRQQGVRLVYSVEDDHLLVTVVAVDKREDGVV
YESAIARLSAAAAALTKALREKLKK

Download         Length: 318 bp

>T203359 NZ_CP099973:836176-836574 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGCTGAAATTCATGCTTGATACCAATACCTGTATTTTCACCATCAAAAATAAGCCCGAACACATCAGAGAACGCTTCAA
CCTCAATACATCCCGAATGTGTATCAGCTCCATCACCTTAATGGAGCTGATTTACGGTGCTGAAAAAAGCCTGGCGCCGG
AGCGTAATCTTGCCGTCGTGGAGGGATTTATCTCCCGCCTTGAGGTTCTGGATTACGATACACAGGCAGCGATACATACC
GGTCAAATCCGTGCCGAACTGGCCCGCAAGGGAACACCTGTCGGGCCTTATGACCAGATGATTGCTGGCCATGCCGGTAG
CCGCGGACTGGTCGTCGTCACAAACAATCTCCGCGAATTTGAACGCATTCCGGGTATCCGAATCGAAGACTGGTGCTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9357.70 Da        Isoelectric Point: 4.6388

>AT203359 WP_226462154.1 NZ_CP075183:c3011024-3010773 [Hydrogenophaga taeniospiralis]
METILADVAVSMSEFKKNPAAVLREANNRPVAVLNHNRAAFYMVEPHLFEAMLEEIADQDLYRKAASRLAEKARAIEVDI
DDL

Download         Length: 252 bp

>AT203359 NZ_CP099973:835949-836176 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGCACACAACACTTTTTTTTAGTAACCGGACCCAGGCAGTCAGATTGCCTAAATCGATATCCTTTCCGGAGGATGTGAA
ACATGTCGAAATCATTGCGGTTGGTAGAAGCAGAATCATTACTCCAGTCGGAGAATCCTGGGACAGCTGGTTCGATGGCG
AAGGCGCCAGTACTGATTTTATGAGTACCAGAGAACAACCCGCAGTACAGGAACGGGAAGGATTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References