Detailed information of TA system TA203347

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): sanaTA/AbiEii-DUF6088
• Location: 3962594..3963932
• Replicon: chromosome
• Accession: NZ_CP075174
• Organism: Salmonella enterica subsp. houtenae serovar 45:gz51:- strain 20-369

Toxin (Protein)

• Gene name: sanaT
• Uniprot ID: -
• Locus tag: KI721_RS19080
• Protein ID: WP_079811715.1
• Coordinates: 3962982..3963932 (+)
• Length: 317 a.a.

Antitoxin (Protein)

• Gene name: sanaA
• Uniprot ID: -
• Locus tag: KI721_RS19075
• Protein ID: WP_134954022.1
• Coordinates: 3962594..3962989 (+)
• Length: 132 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KI721_RS19060 (3960660)	3960660..3960899	+	240	WP_139386631.1	hypothetical protein	-
KI721_RS19065 (3961375)	3961375..3961803	+	429	WP_134954021.1	hypothetical protein	-
KI721_RS19070 (3962074)	3962074..3962340	-	267	WP_000075009.1	hypothetical protein	-
KI721_RS19075 (3962594)	3962594..3962989	+	396	WP_134954022.1	DUF6088 family protein	Antitoxin
KI721_RS19080 (3962982)	3962982..3963932	+	951	WP_079811715.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
KI721_RS19085 (3964336)	3964336..3964803	-	468	WP_079811716.1	helix-turn-helix transcriptional regulator	-
KI721_RS19090 (3965219)	3965219..3966382	-	1164	WP_233679895.1	site-specific integrase	-
KI721_RS19095 (3966611)	3966611..3966895	-	285	Protein_3740	Arm DNA-binding domain-containing protein	-
KI721_RS19105 (3967421)	3967421..3968440	+	1020	WP_079811718.1	NAD(P)-dependent alcohol dehydrogenase	-
KI721_RS19110 (3968471)	3968471..3968779	-	309	Protein_3742	gluconokinase, GntK/IdnK-type	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (38-303)

Antitoxin

• Protein of unknown function DUF6088 (7-109)

Sequences

Toxin

Protein

• Length: 317 a.a.
• Molecular weight: 35776.08 Da
• Isoelectric Point: 6.6431

>T203347 WP_079811715.1 NZ_CP075174:3962982-3963932 [Salmonella enterica subsp. houtenae serovar 45:g,z51:-]
MDNLTLLFSDVADALGIESAAIVEKDHYIVELLRLLKPLTFDTHQLVFAGGTALAKSGIVLNRMSEDVDIKLVPTATFQT
LSRTQRKGIRKEIVQTISSATTETGMFTFDDTHPKVTRDEYRYNDIPVRYPQRVAQAPCLRPFIRLELMEANLLEAPELR
DIHSLVTALTGKTPVISAFPCATITSTQAEKLVAMLRRTAAVARNVERLDDASLVRHIYDTYCIAQTGNVDMRLLTDFFK
RTIEQDIQRYGNQYPQFCVSPNDELKMGLDELERNPLYKTRYQQFVAPMVYGARKVSWDEAYASFRQLALAILNAS

Nucleotide

• Length: 951 bp

>T203347 NZ_CP099965:c542002-541721 [Halomonas sp. DN3]
GTGACGCTGATTGAATGGCGTCCCCAGGCGCGCAAGGCGCTACGGGACATCATCGATTACCTGAGCGACCGCAACCCCCA
AGCCGCGGAAACGCCGTTGTGGTCGATAGAAAAGACGGCCGAAGGTCTTGCCCAACATCCCTACCTTTACCGCCCGGGCA
GAGTCAGGGGGACGCGAGAAGCCGTCGTTCACCCCAACTACCTGATGGTCTACCACATCTCCAACGATCGCATTGTCATC
ATCGACGTACTTCACAGCCGCCAGGAGTACCCCAAGGACTAA

Antitoxin

Protein

• Length: 132 a.a.
• Molecular weight: 14626.91 Da
• Isoelectric Point: 11.1123

>AT203347 WP_134954022.1 NZ_CP075174:3962594-3962989 [Salmonella enterica subsp. houtenae serovar 45:g,z51:-]
MTIKTRIQSRLKRSKRYVFTRDDFKDIAGYDQIGRVLRDLLKEGQLLKVGYGVYTKARRNSITGKVMPAAPGGSSAVLVE
TLDRLKVRYRYVGATQAYNSGESTQIPVSPEIKTSPRFKRALSVGNSKLNG

Nucleotide

• Length: 396 bp

>AT203347 NZ_CP099965:c542204-541989 [Halomonas sp. DN3]
ATGAGCACCCCGCTGGATCACGAGTTCGAGACCCAGGAACAGGTAGACAGCTACGATCGCTGGTTTCGAGAGCGCGTGCA
GCGCAGTCTGGATGATTCACGACCGTCCTTGGCGCACGATGACGTCATGTCTGAAACCCGCACGCTGCTCGAGTCCAAGC
GTGCCTCGAATCCAACTGCGCCTGGAGTCCAAGAAAGGCGCCGTGACGCTGATTGA