203324

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/RHH(antitoxin)
Location 6438527..6439089 Replicon chromosome
Accession NZ_CP075169
Organism Sodalis ligni strain dw23

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag GTU79_RS29960 Protein ID WP_203524267.1
Coordinates 6438527..6438820 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GTU79_RS29965 Protein ID WP_203524268.1
Coordinates 6438808..6439089 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GTU79_RS29920 (GTU79_29905) 6433809..6434690 - 882 WP_214513612.1 Rpn family recombination-promoting nuclease/putative transposase -
GTU79_RS29925 (GTU79_29910) 6434990..6435172 + 183 WP_253073461.1 hypothetical protein -
GTU79_RS29930 (GTU79_29915) 6435272..6435592 - 321 WP_203524261.1 DoxX family protein -
GTU79_RS29935 (GTU79_29920) 6435594..6435974 - 381 WP_203524262.1 DUF4267 domain-containing protein -
GTU79_RS29940 (GTU79_29925) 6436093..6436689 + 597 WP_203524263.1 TetR/AcrR family transcriptional regulator -
GTU79_RS29945 (GTU79_29930) 6436876..6437277 - 402 WP_214513613.1 hypothetical protein -
GTU79_RS29950 (GTU79_29935) 6437589..6437921 - 333 WP_203524265.1 helix-turn-helix transcriptional regulator -
GTU79_RS29955 (GTU79_29940) 6438018..6438276 + 259 Protein_5910 helix-turn-helix transcriptional regulator -
GTU79_RS29960 (GTU79_29945) 6438527..6438820 - 294 WP_203524267.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GTU79_RS29965 (GTU79_29950) 6438808..6439089 - 282 WP_203524268.1 CopG family ribbon-helix-helix protein Antitoxin
GTU79_RS29970 (GTU79_29955) 6439240..6440604 - 1365 WP_203524269.1 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE -
GTU79_RS29975 (GTU79_29960) 6440684..6442330 - 1647 WP_132924067.1 membrane protein insertase YidC -
GTU79_RS29980 (GTU79_29965) 6442333..6442590 - 258 WP_132924066.1 membrane protein insertion efficiency factor YidD -
GTU79_RS29985 (GTU79_29970) 6442554..6442913 - 360 WP_132924065.1 ribonuclease P protein component -
GTU79_RS29990 (GTU79_29975) 6442931..6443074 - 144 WP_132924064.1 50S ribosomal protein L34 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-95)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-42)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11140.71 Da        Isoelectric Point: 7.3155

>T203324 WP_203524267.1 NZ_CP075169:c6438820-6438527 [Sodalis ligni]
MPQVIITQQAATGLTHSREFLTSKNPLAAIRAGQMLEAHFEQRGNNPEMGRPFTELPVLRELKIEFGDSGYVALYRYEKI
EDRVYVLAFRHQKEAGY

Download         Length: 294 bp

>T203324 NZ_CP099912:2406487-2406873 [Escherichia albertii]
ATGATTTGGGTCAGTGCACAGGAGGTCATTGCCTTCCACGATCGAATTTTGCAACGTTTTCCCGGTGTGGCGGGCCTGAC
TGACCCCGGCAGAGCACAGGCGTTGATTTATCGCGTGCAGAATCGTGTTCACTACGAGGGCGTTACTGACCTGTTTGAAC
TGGCAGCAACCTACTGGGTTGCCATCGCTCGCGGTCACATCTTTCATGATGGTAATAAACGTACCGCATTTTTCGTTACT
ATGACCTTTCTTTGGCGCAATGGCATCCGTATCCGTGACGTTGATAACTCGCTGGAGAATCTGACTGTCGAAGCGGCTAC
CGGAGAAAAAACGGTCGGTCAATTAGCGCGATGTTTACGTGAACGAGTGGATAGTTCCGGGAATTAA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10865.14 Da        Isoelectric Point: 5.6113

>AT203324 WP_203524268.1 NZ_CP075169:c6439089-6438808 [Sodalis ligni]
MSTSSTTLKIDDRLKARVKKLADSRDRSPHYLMIAAITQYIEHEEARESFKQEAIDSWREYQETGLHLTGDEVKTWLRGW
GTEVETDIPECHK

Download         Length: 282 bp

>AT203324 NZ_CP099912:2406269-2406490 [Escherichia albertii]
ATGCAAACTTACACTTCCACACAAGCCAGAGCCAATATTGCCACTGTACTGGATACCGCGTTGAATGGTGAGCCAGTTGA
AATCACCCGTCGCGACGGCAGCTCTGCCGTGCTCATTAGTAAAGCCGCATTCGAGGCGTATCAAAATGCGAAACTGGACG
CGGAATTTGATGCCATCATGCAACGTCATGAACACACAATTGAAGCGTTGACTGATCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References