Detailed information of TA system TA203319

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 4555909..4556431
• Replicon: chromosome
• Accession: NZ_CP075169
• Organism: Sodalis ligni strain dw23

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: GTU79_RS21400
• Protein ID: WP_214513342.1
• Coordinates: 4556150..4556431 (+)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: GTU79_RS21395
• Protein ID: WP_203524676.1
• Coordinates: 4555909..4556160 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GTU79_RS21360 (GTU79_21345)	4551253..4552275	+	1023	WP_203524670.1	hypothetical protein	-
GTU79_RS21365 (GTU79_21350)	4552275..4552628	+	354	WP_203524671.1	hypothetical protein	-
GTU79_RS21370 (GTU79_21355)	4552926..4553108	+	183	WP_214513341.1	hypothetical protein	-
GTU79_RS21375 (GTU79_21360)	4553105..4553431	+	327	WP_203524673.1	hypothetical protein	-
GTU79_RS21380 (GTU79_21365)	4553723..4553926	+	204	WP_203524674.1	excisionase	-
GTU79_RS21385 (GTU79_21370)	4553890..4555062	+	1173	WP_203524675.1	site-specific integrase	-
GTU79_RS21390 (GTU79_21375)	4555387..4555677	+	291	Protein_4238	integrase arm-type DNA-binding domain-containing protein	-
GTU79_RS21395 (GTU79_21380)	4555909..4556160	+	252	WP_203524676.1	prevent-host-death protein	Antitoxin
GTU79_RS21400 (GTU79_21385)	4556150..4556431	+	282	WP_214513342.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
GTU79_RS30715	4556643..4556936	+	294	Protein_4241	hypothetical protein	-
GTU79_RS30720	4556958..4557131	+	174	WP_253073390.1	hypothetical protein	-
GTU79_RS30725	4557136..4557276	+	141	WP_253073391.1	hypothetical protein	-
GTU79_RS21415 (GTU79_21400)	4557379..4557644	-	266	Protein_4244	hypothetical protein	-
GTU79_RS21420 (GTU79_21405)	4558122..4558436	+	315	WP_214513343.1	hypothetical protein	-
GTU79_RS21425 (GTU79_21410)	4558727..4559347	+	621	WP_203524773.1	DapH/DapD/GlmU-related protein	-
GTU79_RS21430 (GTU79_21415)	4559496..4560434	-	939	WP_203524681.1	AraC family transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-85)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10773.44 Da
• Isoelectric Point: 9.3330

>T203319 WP_214513342.1 NZ_CP075169:4556150-4556431 [Sodalis ligni]
MSYELEFEEHALKEFKNWARRYGSSSKEVKEILVNPHIPANRLSGMPDCYKIKLRSAGYRLVYQAIDEEVIVLVLAVGKR
ERSEVYNAAKARL

Nucleotide

• Length: 282 bp

>T203319 NZ_CP099912:883554-883958 [Escherichia albertii]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCGCAGTGGCTCTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGCTATTTTACTCATGCCCTGGCCGCTAAGTTATACCCCGTTATGGATGGTGTTGCTTTCGCTGGTGGTGTTTGATTGCG
TCCGCAGTCAGCGGCGCATTAATGCTCGTCAGGGGGAGATTCGCCTGTTGATGGATGGGCGTTTACGCTGGCAGGGGCAG
GAGTGGAGCATCGTCAGAGCGCCGTGGATGATTAAAACTGGCATGATGTTGCGTTTACTCTCTGATAGCGGCAAACGTCA
GCACCTGTGGCTGGCAGCCGACAGTATGGATGAAGCTGAATGGCGGGATTTGCGGCGAATTTTGTTACAACAAGAGATAC
AGTGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9143.51 Da
• Isoelectric Point: 8.4946

>AT203319 WP_203524676.1 NZ_CP075169:4555909-4556160 [Sodalis ligni]
MSVQPILANASVSISDFKKSPNGALKEAHGQPVAVLTNGHISGYYISPETWEAMVDYQEDIELGKIARSRMKGKRVKVKL
DEL

Nucleotide

• Length: 252 bp

>AT203319 NZ_CP099912:883307-883573 [Escherichia albertii]
ATGGACATTAACAATAAAGCCCGCATTCACTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGATAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGACTGCTGGAATGTGACGATCCCGATT
TATTCAACTGGTTGATGAATCACGGTAAACCGGCCGACGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA