Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 3985020..3985615 Replicon chromosome
Accession NZ_CP075169
Organism Sodalis ligni strain dw23

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag GTU79_RS18565 Protein ID WP_203523423.1
Coordinates 3985265..3985615 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag GTU79_RS18560 Protein ID WP_203523422.1
Coordinates 3985020..3985271 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GTU79_RS18530 (GTU79_18520) 3980528..3981109 - 582 WP_203523415.1 dCTP deaminase -
GTU79_RS18535 (GTU79_18525) 3981181..3981822 - 642 WP_203523416.1 uridine kinase -
GTU79_RS18540 (GTU79_18530) 3982270..3982926 + 657 WP_214513253.1 phosphatase PAP2 family protein -
GTU79_RS18545 (GTU79_18535) 3982994..3983164 - 171 WP_203523418.1 hypothetical protein -
GTU79_RS18550 (GTU79_18540) 3983416..3983898 - 483 WP_203523419.1 hypothetical protein -
GTU79_RS30690 3984127..3984422 - 296 Protein_3685 XRE family transcriptional regulator -
GTU79_RS18555 (GTU79_18545) 3984398..3984772 - 375 Protein_3686 type II toxin-antitoxin system RelE/ParE family toxin -
GTU79_RS18560 (GTU79_18550) 3985020..3985271 + 252 WP_203523422.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
GTU79_RS18565 (GTU79_18555) 3985265..3985615 + 351 WP_203523423.1 type II toxin-antitoxin system ChpB family toxin Toxin
GTU79_RS18570 (GTU79_18560) 3985716..3986126 - 411 WP_203523424.1 type II toxin-antitoxin system VapC family toxin -
GTU79_RS18575 (GTU79_18565) 3986128..3986379 - 252 WP_203523425.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
GTU79_RS18580 (GTU79_18570) 3986515..3987627 - 1113 WP_203523426.1 iron-sulfur cluster carrier protein ApbC -
GTU79_RS18585 (GTU79_18575) 3987767..3989812 + 2046 WP_203523427.1 methionine--tRNA ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-112)

Antitoxin

SpoVT-AbrB domain

(6-49)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12432.35 Da        Isoelectric Point: 5.1617

>T203317 WP_203523423.1 NZ_CP075169:3985265-3985615 [Sodalis ligni]
MVKRPGFQRGDIVIEAFNPVVGREEQGIERPALVLSTRDFNRLGMVLVAPITQGGNFAREAGFAVSLTGAGTRTQGVALI
NQVRMLDLSSRAAKIIEKAPEEVTDEALAILDAIIS

Download         Length: 351 bp

>T203317 NZ_CP099912:138562-138747 [Escherichia albertii]
GTGAAAAGTGCAGACGTGATCGCCATCCTGAAGCAGCATGGCTGGGAACATATTCGAACCCGTGGCAGTCATCATCAGTT
CCGCCACCCTGTTCATCCGGGTCTGGTGACGGTTCCGCACCCTAAAAAAGATATTAAGCCCGGTACGCTGGCGCAAATTG
GGCGTCAGGCTGGTTTAACATTTTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9223.61 Da        Isoelectric Point: 4.7513

>AT203317 WP_203523422.1 NZ_CP075169:3985020-3985271 [Sodalis ligni]
MRIAIKKWGNSAGMIIPAQVLEQLHLQVGQELFAEIRGDELILKSGKRKYTLAELIAECDPEASPASDMAIWQGSDQKGN
EVW

Download         Length: 252 bp

>AT203317 NZ_CP099912:138764-139174 [Escherichia albertii]
ATGTTTTATCCCGCCTATATCCACAGTGATCCTGACGGCAGCGCCAGCGGTTTTTTCCCTGATGTTCCAGGCTGTTATTT
TGCTGGGGATACGCTGGACAACGCTTTCCAGGATGCGCGAAGTGCACTGGTCGCGCACTTCGAAACCTTATGCGAGATGA
ATGAAGAGTTGCCGCTTCCAGGCTCTGTGGAAACACATCTGGTTCAGCGTGCGCAGGACTTTATTGGCGGGCAATGGTTG
CTGGTGGATATCAATATGAATCAGTTCGAAGGTCGGGCTGAACGTATCAATATTACGATGCCAAAAAGATTACTGAACAA
GATTGATACCTACGTGCGCAATAACCCAGACTACGCCAACAGAAGTGCGTTTCTGGCGGAAGCTGCCCGGCGTGTATTGC
CGGGCGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References