Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4606881..4607244 Replicon chromosome
Accession NZ_CP075146
Organism Xanthomonas campestris pv. campestris strain GBBC1458

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag KIV67_RS20065 Protein ID WP_011270059.1
Coordinates 4606881..4607015 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag KIV67_RS20070 Protein ID WP_011038999.1
Coordinates 4607092..4607244 (-) Length 51 a.a.

Genomic Context

KIV67_RS20080KIV67_RS20085KIV67_RS20090KIV67_RS20095KIV67_RS20100KIV67_RS20045KIV67_RS20050KIV67_RS20055KIV67_RS20060KIV67_RS20065KIV67_RS20070KIV67_RS20075
Location: 4608592..4609053 (462 bp)
Type: Others
Protein ID: WP_011039001.1
Location: 4609136..4609495 (360 bp)
Type: Others
Protein ID: WP_011039002.1
Location: 4609598..4610515 (918 bp)
Type: Others
Protein ID: WP_011039003.1
Location: 4610512..4611054 (543 bp)
Type: Others
Protein ID: WP_237350319.1
Location: 4611389..4612072 (684 bp)
Type: Others
Protein ID: WP_011039005.1
Location: 4602145..4603797 (1653 bp)
Type: Others
Protein ID: WP_043877841.1
Location: 4603962..4604906 (945 bp)
Type: Others
Protein ID: WP_043877842.1
Location: 4604990..4606279 (1290 bp)
Type: Others
Protein ID: WP_029629069.1
Location: 4606439..4606648 (210 bp)
Type: Others
Protein ID: WP_011038998.1
Location: 4606881..4607015 (135 bp)
Type: Toxin
Protein ID: WP_011270059.1
Location: 4607092..4607244 (153 bp)
Type: Antitoxin
Protein ID: WP_011038999.1
Location: 4607355..4608278 (924 bp)
Type: Others
Protein ID: WP_011039000.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
KIV67_RS20045 (KIV67_20055)4602145..4603797-1653WP_043877841.1M28 family metallopeptidase-
KIV67_RS20050 (KIV67_20060)4603962..4604906-945WP_043877842.1MBL fold metallo-hydrolase-
KIV67_RS20055 (KIV67_20065)4604990..4606279-1290WP_029629069.1tryptophan--tRNA ligase-
KIV67_RS20060 (KIV67_20070)4606439..4606648-210WP_011038998.1CsbD family protein-
KIV67_RS20065 (KIV67_20075)4606881..4607015-135WP_011270059.1entericidin A/B family lipoproteinToxin
KIV67_RS20070 (KIV67_20080)4607092..4607244-153WP_011038999.1entericidin A/B family lipoproteinAntitoxin
KIV67_RS20075 (KIV67_20085)4607355..4608278-924WP_011039000.1arginase-
KIV67_RS20080 (KIV67_20090)4608592..4609053+462WP_011039001.1roadblock/LC7 domain-containing protein-
KIV67_RS20085 (KIV67_20095)4609136..4609495+360WP_011039002.1hypothetical protein-
KIV67_RS20090 (KIV67_20100)4609598..4610515+918WP_011039003.1hypothetical protein-
KIV67_RS20095 (KIV67_20105)4610512..4611054+543WP_237350319.1ATP/GTP-binding protein-
KIV67_RS20100 (KIV67_20110)4611389..4612072+684WP_011039005.1dTMP kinase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T203298 WP_011270059.1 NZ_CP075146:c4607015-4606881 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T203298 NZ_CP099908:c15948-15532 [Escherichia albertii]
GTGAACAAGATCTATATGCTCGACACCAACATCTGCTCGTTCATCATGCGCGAGCAGCCGGAAGCGGTGCTGAAGCGCCT
GGAGCAGGCGGTGCTGCGCGGCCACCGTATCGTGGTCTCGGCCATCACCTACTCCGAGATGCGCTTCGGCGCCACCGGCC
CGAAGGCCTCGCCGCGCCACGTTCAGCTGGTTGACGCATTCTGTGAGCGACTCGATGCCGTCCTGCCCTGGGATCGCGCC
GCGGTGGATGCGACCACAGAGATTAAGGTGGCGCTGCGCCTCGCCGGAACGCCGATAGGCCCGAACGACACGGCGATTTC
CGGACACGCCATCGCGGCGGGCGCCATCCTGGTGACGAATAATACAAGAGAGTTTGAGCGGGTTCCGGGCCTGATACTGG
AAGACTGGGCCGGTTAG

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT203298 WP_011038999.1 NZ_CP075146:c4607244-4607092 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT203298 NZ_CP099908:c16175-15945 [Escherichia albertii]
ATGAGAACCGTATCGATATTTAAAAATGGCAACAACCGTGCCATCCGTCTGCCCCGGGATCTGGATTTTGAGGGAGTGAG
CGAGCTGGAGATCGTCCGGGAAGGGGGCAGCATCATCCTGCGTCCCGTCCGACCGACCTGGGGCTCGTTCGCGCAGCTCG
AAAAAGCTGACCCGGACTTTATGGCGGAGCGCGAGGACGTTATCAGCGACGAAGGACGATTTAACCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A0H2XDQ0

Antitoxin

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Source
ID
Structure
AlphaFold DBQ8P3Z2

References