203298

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4606881..4607244 Replicon chromosome
Accession NZ_CP075146
Organism Xanthomonas campestris pv. campestris strain GBBC1458

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag KIV67_RS20065 Protein ID WP_011270059.1
Coordinates 4606881..4607015 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag KIV67_RS20070 Protein ID WP_011038999.1
Coordinates 4607092..4607244 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KIV67_RS20045 (KIV67_20055) 4602145..4603797 - 1653 WP_043877841.1 M28 family metallopeptidase -
KIV67_RS20050 (KIV67_20060) 4603962..4604906 - 945 WP_043877842.1 MBL fold metallo-hydrolase -
KIV67_RS20055 (KIV67_20065) 4604990..4606279 - 1290 WP_029629069.1 tryptophan--tRNA ligase -
KIV67_RS20060 (KIV67_20070) 4606439..4606648 - 210 WP_011038998.1 CsbD family protein -
KIV67_RS20065 (KIV67_20075) 4606881..4607015 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
KIV67_RS20070 (KIV67_20080) 4607092..4607244 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
KIV67_RS20075 (KIV67_20085) 4607355..4608278 - 924 WP_011039000.1 arginase -
KIV67_RS20080 (KIV67_20090) 4608592..4609053 + 462 WP_011039001.1 roadblock/LC7 domain-containing protein -
KIV67_RS20085 (KIV67_20095) 4609136..4609495 + 360 WP_011039002.1 hypothetical protein -
KIV67_RS20090 (KIV67_20100) 4609598..4610515 + 918 WP_011039003.1 hypothetical protein -
KIV67_RS20095 (KIV67_20105) 4610512..4611054 + 543 WP_237350319.1 ATP/GTP-binding protein -
KIV67_RS20100 (KIV67_20110) 4611389..4612072 + 684 WP_011039005.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T203298 WP_011270059.1 NZ_CP075146:c4607015-4606881 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T203298 NZ_CP099908:c15948-15532 [Escherichia albertii]
GTGAACAAGATCTATATGCTCGACACCAACATCTGCTCGTTCATCATGCGCGAGCAGCCGGAAGCGGTGCTGAAGCGCCT
GGAGCAGGCGGTGCTGCGCGGCCACCGTATCGTGGTCTCGGCCATCACCTACTCCGAGATGCGCTTCGGCGCCACCGGCC
CGAAGGCCTCGCCGCGCCACGTTCAGCTGGTTGACGCATTCTGTGAGCGACTCGATGCCGTCCTGCCCTGGGATCGCGCC
GCGGTGGATGCGACCACAGAGATTAAGGTGGCGCTGCGCCTCGCCGGAACGCCGATAGGCCCGAACGACACGGCGATTTC
CGGACACGCCATCGCGGCGGGCGCCATCCTGGTGACGAATAATACAAGAGAGTTTGAGCGGGTTCCGGGCCTGATACTGG
AAGACTGGGCCGGTTAG

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT203298 WP_011038999.1 NZ_CP075146:c4607244-4607092 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT203298 NZ_CP099908:c16175-15945 [Escherichia albertii]
ATGAGAACCGTATCGATATTTAAAAATGGCAACAACCGTGCCATCCGTCTGCCCCGGGATCTGGATTTTGAGGGAGTGAG
CGAGCTGGAGATCGTCCGGGAAGGGGGCAGCATCATCCTGCGTCCCGTCCGACCGACCTGGGGCTCGTTCGCGCAGCTCG
AAAAAGCTGACCCGGACTTTATGGCGGAGCGCGAGGACGTTATCAGCGACGAAGGACGATTTAACCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References