Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2600104..2600375 Replicon chromosome
Accession NC_002655
Organism Escherichia coli O157:H7 str. EDL933

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2600142..2600245 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2600104..2600375 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Z_RS13535 (Z2882) 2597261..2598700 + 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
Z_RS13540 (Z2883) 2598818..2599054 + 237 WP_001295499.1 DUF1480 family protein -
Z_RS13545 (Z2884) 2599159..2599350 + 192 WP_001296140.1 YebW family protein -
Z_RS13550 (Z2885) 2599351..2600007 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 2600104..2600375 + 272 - - Antitoxin
- 2600142..2600245 - 104 - - Toxin
Z_RS13560 (Z2887) 2600403..2600744 - 342 WP_000976483.1 YebY family protein -
Z_RS13565 (Z2888) 2600757..2601629 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
Z_RS13570 (Z2889) 2601633..2602007 - 375 WP_000168751.1 CopC domain-containing protein YobA -
Z_RS13575 (Z2891) 2602146..2602376 + 231 WP_000916763.1 DNA polymerase III subunit theta -
Z_RS13580 (Z2893) 2602478..2603134 + 657 WP_000119267.1 carbon-nitrogen hydrolase family protein -
Z_RS13585 (Z2894) 2603158..2603820 + 663 WP_000944243.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T20322 NC_002655:c2600245-2600142 [Escherichia coli O157:H7 str. EDL933]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT20322 NC_002655:2600104-2600375 [Escherichia coli O157:H7 str. EDL933]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References