Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2105477..2105620 Replicon chromosome
Accession NZ_CP075135
Organism Salmonella enterica strain CFSAN044888

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2105515..2105618 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2105477..2105620 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A7S10_RS10065 2101902..2102600 - 699 WP_000944280.1 exodeoxyribonuclease X -
A7S10_RS10070 2102624..2103280 - 657 WP_000100257.1 carbon-nitrogen hydrolase family protein -
A7S10_RS10075 2103387..2103617 - 231 WP_000856225.1 DNA polymerase III subunit theta -
A7S10_RS10080 2103755..2104129 + 375 WP_000168393.1 CopC domain-containing protein YobA -
A7S10_RS10085 2104130..2105005 + 876 WP_000979696.1 copper homeostasis membrane protein CopD -
A7S10_RS10090 2105022..2105375 + 354 WP_000722368.1 YebY family protein -
- 2105477..2105620 - 144 - - Antitoxin
- 2105515..2105618 + 104 - - Toxin
A7S10_RS10095 2105758..2106837 - 1080 Protein_1983 phage integrase Arm DNA-binding domain-containing protein -
A7S10_RS10100 2106870..2108018 - 1149 Protein_1984 PD-(D/E)XK nuclease-like domain-containing protein -
A7S10_RS10105 2108010..2108258 + 249 Protein_1985 glycoside hydrolase family 19 protein -
A7S10_RS10110 2108255..2108788 + 534 WP_001529209.1 DUF2514 domain-containing protein -
A7S10_RS10115 2109057..2109224 - 168 WP_000789530.1 lytic enzyme -
A7S10_RS10120 2109527..2110018 + 492 WP_001629197.1 DUF1441 family protein -
A7S10_RS10125 2110110..2110572 + 463 Protein_1989 phage terminase large subunit family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 2083606..2138626 55020


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T203196 NZ_CP075135:2105515-2105618 [Salmonella enterica]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 144 bp

>AT203196 NZ_CP075135:c2105620-2105477 [Salmonella enterica]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References