Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relB-parE/ParE-RHH |
| Location | 1970188..1970750 | Replicon | chromosome |
| Accession | NC_002488 | ||
| Organism | Xylella fastidiosa 9a5c | ||
Toxin (Protein)
| Gene name | parE | Uniprot ID | Q9PBR6 |
| Locus tag | XF_RS09000 | Protein ID | WP_010894527.1 |
| Coordinates | 1970188..1970484 (-) | Length | 99 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | Q9PBR5 |
| Locus tag | XF_RS09005 | Protein ID | WP_010894528.1 |
| Coordinates | 1970472..1970750 (-) | Length | 93 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| XF_RS08950 (XF2062) | 1965266..1965475 | + | 210 | WP_010894516.1 | hypothetical protein | - |
| XF_RS08955 (XF2063) | 1965505..1966040 | - | 536 | Protein_1766 | recombinase family protein | - |
| XF_RS08960 (XF2064) | 1966034..1966237 | - | 204 | WP_023906434.1 | hypothetical protein | - |
| XF_RS08965 (XF2065) | 1966289..1966558 | - | 270 | WP_010894518.1 | hypothetical protein | - |
| XF_RS08970 (XF2066) | 1966667..1966975 | - | 309 | WP_010894519.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| XF_RS08975 (XF2067) | 1966979..1967251 | - | 273 | WP_010894520.1 | hypothetical protein | - |
| XF_RS08980 (XF2068) | 1967248..1967703 | - | 456 | WP_010894521.1 | hypothetical protein | - |
| XF_RS14155 | 1968112..1968546 | - | 435 | Protein_1772 | hypothetical protein | - |
| XF_RS14415 | 1968596..1968853 | - | 258 | WP_140190226.1 | hypothetical protein | - |
| XF_RS08990 | 1969008..1969296 | - | 289 | Protein_1774 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| XF_RS13540 (XF2071) | 1969289..1969531 | - | 243 | WP_010894524.1 | type II toxin-antitoxin system ParD family antitoxin | - |
| XF_RS09000 (XF2074) | 1970188..1970484 | - | 297 | WP_010894527.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| XF_RS09005 (XF2075) | 1970472..1970750 | - | 279 | WP_010894528.1 | CopG family ribbon-helix-helix protein | Antitoxin |
| XF_RS14710 | 1971279..1971536 | + | 258 | WP_209320004.1 | transposase | - |
| XF_RS09015 (XF2077) | 1971533..1972192 | + | 660 | WP_010894530.1 | hypothetical protein | - |
| XF_RS09020 (XF2078) | 1972212..1972574 | + | 363 | WP_143704175.1 | hypothetical protein | - |
| XF_RS13555 (XF2080) | 1972992..1973357 | - | 366 | WP_196489786.1 | type II toxin-antitoxin system YafQ family toxin | - |
| XF_RS09035 (XF2081) | 1973260..1973520 | - | 261 | WP_010894534.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | - |
| XF_RS09040 (XF2082) | 1973850..1974656 | - | 807 | WP_010894535.1 | oxidoreductase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 99 a.a. Molecular weight: 11155.72 Da Isoelectric Point: 7.4670
>T20285 WP_010894527.1 NC_002488:c1970484-1970188 [Xylella fastidiosa 9a5c]
MPRVIFAPEAILNIQRLRNFLHPKNTDAARRAGEAIMRGARMLGAQPHIGRPVDDMPDEYREWLIDFGDSGYVARYHIDG
DTVTILAVRHHKEVGYTS
MPRVIFAPEAILNIQRLRNFLHPKNTDAARRAGEAIMRGARMLGAQPHIGRPVDDMPDEYREWLIDFGDSGYVARYHIDG
DTVTILAVRHHKEVGYTS
Download Length: 297 bp
>T20285 NC_002488:c1970484-1970188 [Xylella fastidiosa 9a5c]
ATGCCACGGGTGATCTTCGCTCCCGAAGCCATCCTGAACATTCAACGATTGCGGAATTTCCTGCATCCGAAGAACACCGA
TGCCGCAAGGCGGGCCGGTGAAGCCATCATGCGGGGTGCGCGGATGCTTGGAGCGCAGCCACATATCGGTCGTCCGGTTG
ATGATATGCCCGATGAGTACAGGGAATGGCTGATTGACTTCGGAGATAGCGGTTATGTGGCCCGCTACCACATTGATGGC
GATACCGTCACGATCTTGGCTGTTCGACACCATAAGGAAGTGGGATACACCAGCTGA
ATGCCACGGGTGATCTTCGCTCCCGAAGCCATCCTGAACATTCAACGATTGCGGAATTTCCTGCATCCGAAGAACACCGA
TGCCGCAAGGCGGGCCGGTGAAGCCATCATGCGGGGTGCGCGGATGCTTGGAGCGCAGCCACATATCGGTCGTCCGGTTG
ATGATATGCCCGATGAGTACAGGGAATGGCTGATTGACTTCGGAGATAGCGGTTATGTGGCCCGCTACCACATTGATGGC
GATACCGTCACGATCTTGGCTGTTCGACACCATAAGGAAGTGGGATACACCAGCTGA
Antitoxin
Download Length: 93 a.a. Molecular weight: 10772.08 Da Isoelectric Point: 5.6126
>AT20285 WP_010894528.1 NC_002488:c1970750-1970472 [Xylella fastidiosa 9a5c]
MGMATSIKLDDELKGRVQHLADVRRRTSHWIMREAIAQYVEREEKRETFRQDTLKAWEEFQATGLHVTTEEVEKWLSSWG
TENELSAPVCHG
MGMATSIKLDDELKGRVQHLADVRRRTSHWIMREAIAQYVEREEKRETFRQDTLKAWEEFQATGLHVTTEEVEKWLSSWG
TENELSAPVCHG
Download Length: 279 bp
>AT20285 NC_002488:c1970750-1970472 [Xylella fastidiosa 9a5c]
ATGGGCATGGCAACCTCCATCAAGCTTGATGATGAGCTGAAAGGACGTGTGCAGCATCTGGCCGATGTTCGCCGCCGCAC
TTCGCACTGGATCATGCGCGAGGCGATCGCGCAGTACGTTGAGCGTGAGGAAAAGCGTGAGACGTTTCGGCAGGACACGC
TGAAGGCATGGGAAGAGTTTCAGGCGACCGGCCTGCACGTGACGACCGAAGAAGTCGAGAAGTGGCTTTCGAGTTGGGGC
ACTGAAAATGAATTGTCAGCGCCCGTATGCCACGGGTGA
ATGGGCATGGCAACCTCCATCAAGCTTGATGATGAGCTGAAAGGACGTGTGCAGCATCTGGCCGATGTTCGCCGCCGCAC
TTCGCACTGGATCATGCGCGAGGCGATCGCGCAGTACGTTGAGCGTGAGGAAAAGCGTGAGACGTTTCGGCAGGACACGC
TGAAGGCATGGGAAGAGTTTCAGGCGACCGGCCTGCACGTGACGACCGAAGAAGTCGAGAAGTGGCTTTCGAGTTGGGGC
ACTGAAAATGAATTGTCAGCGCCCGTATGCCACGGGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A1S0VAK4 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A1S0V821 |