Detailed information of TA system TA020282

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pasB-vapB/RelE-VagC
• Location: 1620593..1621091
• Replicon: chromosome
• Accession: NC_002488
• Organism: Xylella fastidiosa 9a5c

Toxin (Protein)

• Gene name: pasB
• Uniprot ID: -
• Locus tag: XF_RS07235
• Protein ID: WP_042463219.1
• Coordinates: 1620816..1621091 (-)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: XF_RS13325
• Protein ID: WP_209320000.1
• Coordinates: 1620593..1620778 (-)
• Length: 62 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
XF_RS07215 (XF1689)	1616967..1617404	+	438	WP_010894081.1	DUF3277 family protein	-
XF_RS07220 (XF1690)	1617401..1617823	+	423	WP_010894082.1	hypothetical protein	-
XF_RS07225 (XF1692)	1617971..1619860	+	1890	WP_010894164.1	hypothetical protein	-
XF_RS14075 (XF1693)	1620190..1620366	+	177	WP_088371569.1	Blp family class II bacteriocin	-
XF_RS13320 (XF1694)	1620400..1620588	+	189	WP_010894166.1	hypothetical protein	-
XF_RS13325 (XF1695)	1620593..1620778	-	186	WP_209320000.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
XF_RS07235	1620816..1621091	-	276	WP_042463219.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
XF_RS07240 (XF1696)	1621075..1621365	-	291	WP_196432179.1	CopG family transcriptional regulator	-
XF_RS07245 (XF1697)	1621413..1622183	+	771	WP_010894169.1	hypothetical protein	-
XF_RS07250 (XF1698)	1622183..1622500	+	318	WP_010894170.1	hypothetical protein	-
XF_RS07255 (XF1699)	1622497..1623327	+	831	WP_010894171.1	hypothetical protein	-
XF_RS07260 (XF1700)	1623324..1623965	+	642	WP_010894172.1	hypothetical protein	-
XF_RS07265 (XF1701)	1623962..1624315	+	354	WP_010894173.1	hypothetical protein	-
XF_RS07270 (XF1702)	1624326..1624631	-	306	WP_004089254.1	putative addiction module antidote protein	-
XF_RS07275 (XF1703)	1624628..1624930	-	303	WP_042463224.1	type II toxin-antitoxin system RelE/ParE family toxin	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-86)

Antitoxin

• SpoVT-AbrB domain (21-59)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10471.13 Da
• Isoelectric Point: 10.0494

>T20282 WP_042463219.1 NC_002488:c1621091-1620816 [Xylella fastidiosa 9a5c]
MAWTIDYTDTAKQQLRKLDKHMARRIVDFMDERIAGLENPRSSGKALTGPLGGFWRYRVGDFRVVCAIQDSVLRVLVVGV
GHRGEMYRREC

Nucleotide

• Length: 276 bp

>T20282 NC_002488:c1621091-1620816 [Xylella fastidiosa 9a5c]
TTGGCCTGGACGATTGATTACACCGACACGGCCAAGCAGCAGTTACGCAAACTCGACAAGCACATGGCGCGGCGCATTGT
CGATTTCATGGATGAGCGCATCGCCGGACTAGAAAACCCACGCAGCAGTGGTAAAGCATTAACCGGACCACTTGGCGGCT
TTTGGCGTTATCGTGTTGGTGATTTCCGGGTCGTCTGCGCCATTCAAGATAGCGTTTTGCGCGTCCTTGTGGTGGGTGTT
GGTCACCGGGGTGAGATGTACCGACGAGAATGCTAG

Antitoxin

Protein

• Length: 62 a.a.
• Molecular weight: 6964.12 Da
• Isoelectric Point: 8.9195

>AT20282 WP_209320000.1 NC_002488:c1620778-1620593 [Xylella fastidiosa 9a5c]
MGTVPMPISSPLSRTKEAKLFRNNRSQVVRIPVEFELPGDRVLIHPEEDKLIIEPITRPTN

Nucleotide

• Length: 186 bp

>AT20282 NC_002488:c1620778-1620593 [Xylella fastidiosa 9a5c]
ATGGGTACCGTGCCGATGCCAATTTCATCTCCGTTATCACGTACCAAGGAAGCGAAGCTATTCCGAAATAATCGTAGCCA
GGTGGTACGAATTCCCGTTGAATTCGAGCTGCCGGGTGATCGTGTTCTGATCCACCCTGAGGAGGACAAGCTCATTATTG
AGCCGATCACCCGGCCAACCAACTAA