Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasB-vapB/RelE-VagC
Location 1620593..1621091 Replicon chromosome
Accession NC_002488
Organism Xylella fastidiosa 9a5c

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag XF_RS07235 Protein ID WP_042463219.1
Coordinates 1620816..1621091 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag XF_RS13325 Protein ID WP_209320000.1
Coordinates 1620593..1620778 (-) Length 62 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XF_RS07215 (XF1689) 1616967..1617404 + 438 WP_010894081.1 DUF3277 family protein -
XF_RS07220 (XF1690) 1617401..1617823 + 423 WP_010894082.1 hypothetical protein -
XF_RS07225 (XF1692) 1617971..1619860 + 1890 WP_010894164.1 hypothetical protein -
XF_RS14075 (XF1693) 1620190..1620366 + 177 WP_088371569.1 Blp family class II bacteriocin -
XF_RS13320 (XF1694) 1620400..1620588 + 189 WP_010894166.1 hypothetical protein -
XF_RS13325 (XF1695) 1620593..1620778 - 186 WP_209320000.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
XF_RS07235 1620816..1621091 - 276 WP_042463219.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
XF_RS07240 (XF1696) 1621075..1621365 - 291 WP_196432179.1 CopG family transcriptional regulator -
XF_RS07245 (XF1697) 1621413..1622183 + 771 WP_010894169.1 hypothetical protein -
XF_RS07250 (XF1698) 1622183..1622500 + 318 WP_010894170.1 hypothetical protein -
XF_RS07255 (XF1699) 1622497..1623327 + 831 WP_010894171.1 hypothetical protein -
XF_RS07260 (XF1700) 1623324..1623965 + 642 WP_010894172.1 hypothetical protein -
XF_RS07265 (XF1701) 1623962..1624315 + 354 WP_010894173.1 hypothetical protein -
XF_RS07270 (XF1702) 1624326..1624631 - 306 WP_004089254.1 putative addiction module antidote protein -
XF_RS07275 (XF1703) 1624628..1624930 - 303 WP_042463224.1 type II toxin-antitoxin system RelE/ParE family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-86)

Antitoxin

SpoVT-AbrB domain

(21-59)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10471.13 Da        Isoelectric Point: 10.0494

>T20282 WP_042463219.1 NC_002488:c1621091-1620816 [Xylella fastidiosa 9a5c]
MAWTIDYTDTAKQQLRKLDKHMARRIVDFMDERIAGLENPRSSGKALTGPLGGFWRYRVGDFRVVCAIQDSVLRVLVVGV
GHRGEMYRREC

Download         Length: 276 bp

>T20282 NC_002488:c1621091-1620816 [Xylella fastidiosa 9a5c]
TTGGCCTGGACGATTGATTACACCGACACGGCCAAGCAGCAGTTACGCAAACTCGACAAGCACATGGCGCGGCGCATTGT
CGATTTCATGGATGAGCGCATCGCCGGACTAGAAAACCCACGCAGCAGTGGTAAAGCATTAACCGGACCACTTGGCGGCT
TTTGGCGTTATCGTGTTGGTGATTTCCGGGTCGTCTGCGCCATTCAAGATAGCGTTTTGCGCGTCCTTGTGGTGGGTGTT
GGTCACCGGGGTGAGATGTACCGACGAGAATGCTAG

Antitoxin


Download         Length: 62 a.a.        Molecular weight: 6964.12 Da        Isoelectric Point: 8.9195

>AT20282 WP_209320000.1 NC_002488:c1620778-1620593 [Xylella fastidiosa 9a5c]
MGTVPMPISSPLSRTKEAKLFRNNRSQVVRIPVEFELPGDRVLIHPEEDKLIIEPITRPTN

Download         Length: 186 bp

>AT20282 NC_002488:c1620778-1620593 [Xylella fastidiosa 9a5c]
ATGGGTACCGTGCCGATGCCAATTTCATCTCCGTTATCACGTACCAAGGAAGCGAAGCTATTCCGAAATAATCGTAGCCA
GGTGGTACGAATTCCCGTTGAATTCGAGCTGCCGGGTGATCGTGTTCTGATCCACCCTGAGGAGGACAAGCTCATTATTG
AGCCGATCACCCGGCCAACCAACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References