Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2067212..2067357 Replicon chromosome
Accession NZ_CP075106
Organism Salmonella enterica strain CFSAN064276

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2067252..2067355 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2067212..2067357 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CBI76_RS09935 2063638..2064336 - 699 WP_000944282.1 exodeoxyribonuclease X -
CBI76_RS09940 2064360..2065016 - 657 WP_000100257.1 carbon-nitrogen hydrolase family protein -
CBI76_RS09945 2065124..2065354 - 231 WP_000856224.1 DNA polymerase III subunit theta -
CBI76_RS09950 2065492..2065866 + 375 WP_000168393.1 CopC domain-containing protein YobA -
CBI76_RS09955 2065867..2066742 + 876 WP_072101102.1 copper homeostasis membrane protein CopD -
CBI76_RS09960 2066759..2067112 + 354 WP_000722368.1 YebY family protein -
- 2067212..2067357 - 146 - - Antitoxin
- 2067252..2067355 + 104 - - Toxin
CBI76_RS09965 2067484..2068563 - 1080 WP_020438172.1 phage integrase Arm DNA-binding domain-containing protein -
CBI76_RS09970 2068596..2069747 - 1152 Protein_1954 PD-(D/E)XK nuclease-like domain-containing protein -
CBI76_RS09975 2069736..2069927 + 192 Protein_1955 glycoside hydrolase family 19 protein -
CBI76_RS09980 2069981..2070514 + 534 WP_001050883.1 DUF2514 domain-containing protein -
CBI76_RS09985 2070771..2070938 - 168 WP_000789530.1 lytic enzyme -
CBI76_RS09990 2071003..2071191 - 189 WP_001521334.1 hypothetical protein -
CBI76_RS09995 2071246..2071737 + 492 WP_000348541.1 DUF1441 family protein -
CBI76_RS10000 2071724..2072291 + 568 Protein_1960 phage terminase large subunit family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 2061552..2102270 40718


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T202806 NZ_CP075106:2067252-2067355 [Salmonella enterica]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT202806 NZ_CP075106:c2067357-2067212 [Salmonella enterica]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References