Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | FicTA/Fic(toxin) |
| Location | 1595546..1596342 | Replicon | chromosome |
| Accession | NC_002488 | ||
| Organism | Xylella fastidiosa 9a5c | ||
Toxin (Protein)
| Gene name | VbhT | Uniprot ID | Q9PCU8 |
| Locus tag | XF_RS07040 | Protein ID | WP_010894152.1 |
| Coordinates | 1595731..1596342 (+) | Length | 204 a.a. |
Antitoxin (Protein)
| Gene name | VbhA | Uniprot ID | Q9PCU9 |
| Locus tag | XF_RS07035 | Protein ID | WP_010894151.1 |
| Coordinates | 1595546..1595734 (+) | Length | 63 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| XF_RS06995 (XF1648) | 1591171..1592097 | - | 927 | WP_010894143.1 | phage recombination protein Bet | - |
| XF_RS07000 (XF1649) | 1592113..1592934 | - | 822 | WP_010894144.1 | YfdQ family protein | - |
| XF_RS07005 (XF1650) | 1592955..1593329 | - | 375 | WP_010894145.1 | hypothetical protein | - |
| XF_RS07010 (XF1651) | 1593350..1593541 | - | 192 | WP_010894146.1 | hypothetical protein | - |
| XF_RS07015 (XF1652) | 1593565..1593756 | - | 192 | WP_010894147.1 | hypothetical protein | - |
| XF_RS07020 (XF1653) | 1593753..1594154 | - | 402 | WP_010894148.1 | hypothetical protein | - |
| XF_RS07025 (XF1654) | 1594154..1594612 | - | 459 | WP_010894149.1 | hypothetical protein | - |
| XF_RS07030 (XF1655) | 1594609..1595154 | - | 546 | WP_080507209.1 | hypothetical protein | - |
| XF_RS07035 (XF1656) | 1595546..1595734 | + | 189 | WP_010894151.1 | antitoxin VbhA family protein | Antitoxin |
| XF_RS07040 (XF1657) | 1595731..1596342 | + | 612 | WP_010894152.1 | Fic/DOC family protein | Toxin |
| XF_RS07045 (XF1658) | 1596393..1597067 | - | 675 | WP_042463200.1 | helix-turn-helix transcriptional regulator | - |
| XF_RS07050 | 1597152..1597397 | + | 246 | WP_042463203.1 | hypothetical protein | - |
| XF_RS07055 | 1597394..1597699 | - | 306 | WP_042463205.1 | hypothetical protein | - |
| XF_RS07060 | 1597840..1598025 | + | 186 | Protein_1376 | hypothetical protein | - |
| XF_RS07065 (XF1660) | 1598079..1598267 | + | 189 | WP_042463208.1 | hypothetical protein | - |
| XF_RS07070 (XF1661) | 1598264..1598512 | + | 249 | WP_010894156.1 | hypothetical protein | - |
| XF_RS07075 (XF1662) | 1598509..1598892 | + | 384 | WP_042463212.1 | hypothetical protein | - |
| XF_RS07080 (XF1663) | 1599096..1600208 | + | 1113 | WP_042463693.1 | Bro-N domain-containing protein | - |
| XF_RS07085 (XF1664) | 1600205..1600513 | + | 309 | WP_023906549.1 | DUF1376 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 204 a.a. Molecular weight: 22892.65 Da Isoelectric Point: 4.9498
>T20280 WP_010894152.1 NC_002488:1595731-1596342 [Xylella fastidiosa 9a5c]
MKYAGDRGDPYLDSETGVLRNLLGISDQGWLDKIESTLSFLRTSELRERPVKGKFDLAHLQEIHNRLFQDVYDWAGQIRQ
VEISKGNTMFAQQIAIQSAAQQIFGQLAKERFLCGLDAEEFSKRAGDYLGEINVLHPFREGNGRTQREFIAQLAQRAGYR
IDWGVVSQADMIKASIDAYNGDSSGLASIIREGISDQLFKDNE
MKYAGDRGDPYLDSETGVLRNLLGISDQGWLDKIESTLSFLRTSELRERPVKGKFDLAHLQEIHNRLFQDVYDWAGQIRQ
VEISKGNTMFAQQIAIQSAAQQIFGQLAKERFLCGLDAEEFSKRAGDYLGEINVLHPFREGNGRTQREFIAQLAQRAGYR
IDWGVVSQADMIKASIDAYNGDSSGLASIIREGISDQLFKDNE
Download Length: 612 bp
>T20280 NC_002488:1595731-1596342 [Xylella fastidiosa 9a5c]
ATGAAATACGCAGGGGATCGTGGTGATCCTTACCTGGACAGCGAAACAGGTGTTCTTCGTAATCTCCTTGGAATCAGCGA
TCAGGGGTGGCTCGATAAAATAGAGTCCACCCTTTCTTTTTTGCGAACCAGCGAATTGCGTGAGCGACCCGTAAAAGGCA
AATTTGATCTAGCGCATTTACAGGAAATCCATAATCGCCTTTTCCAGGATGTGTACGACTGGGCGGGTCAAATCCGTCAA
GTTGAAATCTCGAAAGGCAACACGATGTTTGCCCAGCAGATTGCGATTCAGAGTGCGGCGCAGCAGATCTTTGGGCAGCT
TGCTAAAGAGCGATTTTTGTGTGGCCTTGATGCTGAGGAATTCAGCAAACGGGCAGGTGATTATCTTGGTGAAATTAATG
TGCTTCACCCATTCCGCGAGGGAAATGGCAGGACGCAACGGGAATTCATCGCGCAATTGGCTCAGCGTGCAGGTTACCGG
ATCGACTGGGGCGTGGTCAGCCAGGCGGATATGATTAAAGCGTCAATCGACGCTTACAACGGGGATTCAAGCGGATTGGC
TAGTATCATTCGCGAAGGAATATCTGATCAGCTTTTTAAAGATAATGAGTAA
ATGAAATACGCAGGGGATCGTGGTGATCCTTACCTGGACAGCGAAACAGGTGTTCTTCGTAATCTCCTTGGAATCAGCGA
TCAGGGGTGGCTCGATAAAATAGAGTCCACCCTTTCTTTTTTGCGAACCAGCGAATTGCGTGAGCGACCCGTAAAAGGCA
AATTTGATCTAGCGCATTTACAGGAAATCCATAATCGCCTTTTCCAGGATGTGTACGACTGGGCGGGTCAAATCCGTCAA
GTTGAAATCTCGAAAGGCAACACGATGTTTGCCCAGCAGATTGCGATTCAGAGTGCGGCGCAGCAGATCTTTGGGCAGCT
TGCTAAAGAGCGATTTTTGTGTGGCCTTGATGCTGAGGAATTCAGCAAACGGGCAGGTGATTATCTTGGTGAAATTAATG
TGCTTCACCCATTCCGCGAGGGAAATGGCAGGACGCAACGGGAATTCATCGCGCAATTGGCTCAGCGTGCAGGTTACCGG
ATCGACTGGGGCGTGGTCAGCCAGGCGGATATGATTAAAGCGTCAATCGACGCTTACAACGGGGATTCAAGCGGATTGGC
TAGTATCATTCGCGAAGGAATATCTGATCAGCTTTTTAAAGATAATGAGTAA
Antitoxin
Download Length: 63 a.a. Molecular weight: 6885.83 Da Isoelectric Point: 4.9859
>AT20280 WP_010894151.1 NC_002488:1595546-1595734 [Xylella fastidiosa 9a5c]
MLTDHEKAERRAVVQSALASQRIEGLEPDAQAVVDAECWARGEMTIATAVDQYKARVRLQMA
MLTDHEKAERRAVVQSALASQRIEGLEPDAQAVVDAECWARGEMTIATAVDQYKARVRLQMA
Download Length: 189 bp
>AT20280 NC_002488:1595546-1595734 [Xylella fastidiosa 9a5c]
ATGCTGACAGATCATGAGAAAGCTGAACGCCGTGCTGTGGTGCAAAGCGCACTCGCAAGCCAACGCATTGAGGGGTTAGA
GCCGGATGCGCAGGCCGTGGTTGATGCTGAATGCTGGGCGCGTGGTGAAATGACTATCGCTACCGCCGTGGACCAGTACA
AAGCGCGTGTTCGGCTCCAGATGGCATGA
ATGCTGACAGATCATGAGAAAGCTGAACGCCGTGCTGTGGTGCAAAGCGCACTCGCAAGCCAACGCATTGAGGGGTTAGA
GCCGGATGCGCAGGCCGTGGTTGATGCTGAATGCTGGGCGCGTGGTGAAATGACTATCGCTACCGCCGTGGACCAGTACA
AAGCGCGTGTTCGGCTCCAGATGGCATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|