Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2076796..2077067 Replicon chromosome
Accession NZ_CP075062
Organism Escherichia coli strain EC_J_9

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2076926..2077029 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2076796..2077067 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H4F96_RS10050 2073351..2074013 - 663 WP_000944256.1 exodeoxyribonuclease X -
H4F96_RS10055 2074037..2074693 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
H4F96_RS10060 2074795..2075025 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H4F96_RS10065 2075164..2075538 + 375 WP_000204699.1 CopC domain-containing protein YobA -
H4F96_RS10070 2075542..2076414 + 873 WP_000879282.1 copper homeostasis membrane protein CopD -
H4F96_RS10075 2076427..2076768 + 342 WP_000976472.1 YebY family protein -
- 2076796..2077067 - 272 - - Antitoxin
- 2076926..2077029 + 104 - - Toxin
H4F96_RS10080 2077164..2077820 + 657 WP_000812735.1 protein-serine/threonine phosphatase -
H4F96_RS10085 2077821..2078012 - 192 WP_001296140.1 YebW family protein -
H4F96_RS10090 2078117..2078353 - 237 WP_001295499.1 YebV family protein -
H4F96_RS10095 2078471..2079910 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T202770 NZ_CP075062:2076926-2077029 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT202770 NZ_CP075062:c2077067-2076796 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References