202625

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2063406..2063677 Replicon chromosome
Accession NZ_CP074680
Organism Escherichia coli strain MEI008

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2063536..2063639 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2063406..2063677 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KIM92_RS09980 2059961..2060623 - 663 WP_000944256.1 exodeoxyribonuclease X -
KIM92_RS09985 2060647..2061303 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
KIM92_RS09990 2061405..2061635 - 231 WP_000916763.1 DNA polymerase III subunit theta -
KIM92_RS09995 2061774..2062148 + 375 WP_000204699.1 CopC domain-containing protein YobA -
KIM92_RS10000 2062152..2063024 + 873 WP_000879282.1 copper homeostasis membrane protein CopD -
KIM92_RS10005 2063037..2063378 + 342 WP_000976472.1 YebY family protein -
- 2063406..2063677 - 272 - - Antitoxin
- 2063536..2063639 + 104 - - Toxin
KIM92_RS10010 2063774..2064430 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
KIM92_RS10015 2064431..2064622 - 192 WP_001296140.1 YebW family protein -
KIM92_RS10020 2064727..2064963 - 237 WP_001295499.1 YebV family protein -
KIM92_RS10025 2065081..2066520 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T202625 NZ_CP074680:2063536-2063639 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT202625 NZ_CP074680:c2063677-2063406 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References