Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1856621..1856766 | Replicon | chromosome |
| Accession | NZ_CP074677 | ||
| Organism | Klebsiella pneumoniae strain MEI009 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1856657..1856759 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1856621..1856766 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KIM99_RS09000 | 1851751..1853811 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| KIM99_RS09005 | 1853815..1854474 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| KIM99_RS09010 | 1854553..1854783 | - | 231 | WP_064181481.1 | DNA polymerase III subunit theta | - |
| KIM99_RS09015 | 1854896..1855270 | + | 375 | WP_064181480.1 | CopC domain-containing protein YobA | - |
| KIM99_RS09020 | 1855274..1856143 | + | 870 | WP_004189267.1 | copper homeostasis membrane protein CopD | - |
| KIM99_RS09025 | 1856160..1856498 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 1856621..1856766 | - | 146 | - | - | Antitoxin |
| - | 1856657..1856759 | + | 103 | - | - | Toxin |
| KIM99_RS09030 | 1857134..1857277 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| KIM99_RS09035 | 1857382..1858350 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| KIM99_RS09040 | 1858507..1859160 | + | 654 | WP_004891053.1 | protein-serine/threonine phosphatase | - |
| KIM99_RS09045 | 1859157..1859348 | - | 192 | WP_002911395.1 | YebW family protein | - |
| KIM99_RS09050 | 1859446..1859685 | - | 240 | WP_002911393.1 | YebV family protein | - |
| KIM99_RS09055 | 1859801..1861234 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T202599 NZ_CP074677:1856657-1856759 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT202599 NZ_CP074677:c1856766-1856621 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT