Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1856621..1856766 Replicon chromosome
Accession NZ_CP074677
Organism Klebsiella pneumoniae strain MEI009

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1856657..1856759 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1856621..1856766 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KIM99_RS09000 1851751..1853811 + 2061 WP_004151449.1 oligopeptidase B -
KIM99_RS09005 1853815..1854474 - 660 WP_002911407.1 exodeoxyribonuclease X -
KIM99_RS09010 1854553..1854783 - 231 WP_064181481.1 DNA polymerase III subunit theta -
KIM99_RS09015 1854896..1855270 + 375 WP_064181480.1 CopC domain-containing protein YobA -
KIM99_RS09020 1855274..1856143 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
KIM99_RS09025 1856160..1856498 + 339 WP_002911404.1 YebY family protein -
- 1856621..1856766 - 146 - - Antitoxin
- 1856657..1856759 + 103 - - Toxin
KIM99_RS09030 1857134..1857277 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KIM99_RS09035 1857382..1858350 - 969 WP_004151446.1 VirK/YbjX family protein -
KIM99_RS09040 1858507..1859160 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
KIM99_RS09045 1859157..1859348 - 192 WP_002911395.1 YebW family protein -
KIM99_RS09050 1859446..1859685 - 240 WP_002911393.1 YebV family protein -
KIM99_RS09055 1859801..1861234 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T202599 NZ_CP074677:1856657-1856759 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT202599 NZ_CP074677:c1856766-1856621 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References