Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 3412658..3413174 Replicon chromosome
Accession NZ_CP074584
Organism Enterobacter asburiae strain L1 delta-T1RM

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KIJ47_RS16195 Protein ID WP_029739265.1
Coordinates 3412658..3412942 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A8E1RL94
Locus tag KIJ47_RS16200 Protein ID WP_023331889.1
Coordinates 3412932..3413174 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KIJ47_RS16180 (KIJ47_16175) 3407935..3409578 + 1644 WP_029739267.1 alpha,alpha-phosphotrehalase -
KIJ47_RS16185 (KIJ47_16180) 3409954..3412092 + 2139 WP_023310191.1 anaerobic ribonucleoside-triphosphate reductase -
KIJ47_RS16190 (KIJ47_16185) 3412190..3412654 + 465 WP_029739266.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
KIJ47_RS16195 (KIJ47_16190) 3412658..3412942 - 285 WP_029739265.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KIJ47_RS16200 (KIJ47_16195) 3412932..3413174 - 243 WP_023331889.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
KIJ47_RS16205 (KIJ47_16200) 3413252..3415162 - 1911 WP_029739264.1 PRD domain-containing protein -
KIJ47_RS16210 (KIJ47_16205) 3415182..3416318 - 1137 WP_029739263.1 lactonase family protein -
KIJ47_RS16215 (KIJ47_16210) 3416402..3417142 - 741 WP_029739262.1 KDGP aldolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-69)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10873.72 Da        Isoelectric Point: 10.3350

>T202491 WP_029739265.1 NZ_CP074584:c3412942-3412658 [Enterobacter asburiae]
MTYELAFDPRALKEWSKLGQTVKDQLKKKLAEVLVNPRVESARLHGLPDCYKIKLRSQGYRLVYQVQDNVVTVFVIAIGK
REKSAVYHDANKRL

Download         Length: 285 bp

>T202491 NZ_CP099464:2206517-2206897 [Dolichospermum heterosporum TAC447]
ATAAATGAAAAACCTCTCAAATGGGTTGCAAGCGCACTTGACGATTTAAAGGAGTTTCCTGAAGATGTACAAGACGTAAT
GGGTTACGCTCTTGACTTAGCGCAACACGGTCAAAAACACCCTGACGCGAAACCTTTAAAGGGTTTTCCAGAATCGGGTG
TTGTGGAAATTGTAGATGATTTTGATGGGGATACATATAGAGCAATTTACACCGTTAAATTTAAAGGTGTTATTTACTTG
TTACATTCTTTTCAGAAGAAGTCAAAACATGGTATTGCTACACCACAACAAGATATAGATTTGGTAAGAAAAAGACTGAA
AACTGCTGAATTAGATTACTTACAAGAAACTGCTCAAAAAAATGGAGTAAAAAATGGATAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9030.41 Da        Isoelectric Point: 4.7719

>AT202491 WP_023331889.1 NZ_CP074584:c3413174-3412932 [Enterobacter asburiae]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRMPVKTVTISDSEDELIQTVRERLANPQKGIKVSLDDL

Download         Length: 243 bp

>AT202491 NZ_CP099464:2206890-2207216 [Dolichospermum heterosporum TAC447]
ATGGATAGTGAAAATAGAATTACTGTTAGCAGTGGAAATGTATTTGCTGATTTGGGTTTAGCTAATTCTGAAGAAAGATT
ATTGAAAGCTGAACTAGCACGTAAAATCAGTGAAATTATCAATAGTCAAAAATTAACACAAGTTCAAGCTGCTGAAATTT
TAGGAATAGATCAACCAAAGGTTTCTCTGCTAATTAGAGGTAGACTAAGTGGCTTTTCAACCGATAGATTGATGGCTTAT
CTTAACAAATTAGGTAGTGATGTAGAAATTACAGTTAAACCTAAACCTGAAAATCACAAATTTGCCCGTACAACTGTAGT
TTGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References