Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4870703..4870848 Replicon chromosome
Accession NZ_CP074580
Organism Klebsiella pneumoniae strain B30155

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4870739..4870841 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4870703..4870848 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KH752_RS23345 (KH752_23345) 4865833..4867893 + 2061 WP_004148850.1 oligopeptidase B -
KH752_RS23350 (KH752_23350) 4867897..4868556 - 660 WP_134919889.1 exodeoxyribonuclease X -
KH752_RS23355 (KH752_23355) 4868635..4868865 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KH752_RS23360 (KH752_23360) 4868978..4869352 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KH752_RS23365 (KH752_23365) 4869356..4870225 + 870 WP_004891049.1 copper homeostasis membrane protein CopD -
KH752_RS23370 (KH752_23370) 4870242..4870580 + 339 WP_002911404.1 YebY family protein -
- 4870703..4870848 - 146 - - Antitoxin
- 4870739..4870841 + 103 - - Toxin
KH752_RS23375 (KH752_23375) 4871216..4871359 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KH752_RS23380 (KH752_23380) 4871464..4872432 - 969 WP_014907334.1 VirK/YbjX family protein -
KH752_RS23385 (KH752_23385) 4872589..4873242 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
KH752_RS23390 (KH752_23390) 4873239..4873430 - 192 WP_002911395.1 YebW family protein -
KH752_RS23395 (KH752_23395) 4873528..4873767 - 240 WP_002911393.1 YebV family protein -
KH752_RS23400 (KH752_23400) 4873883..4875316 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T202469 NZ_CP074580:4870739-4870841 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT202469 NZ_CP074580:c4870848-4870703 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References