Detailed information of TA system TA202456

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-RHH
• Location: 1858840..1859353
• Replicon: chromosome
• Accession: NZ_CP074578
• Organism: Pseudomonas syringae strain Susan2139

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: KIJ28_RS08280
• Protein ID: WP_103363385.1
• Coordinates: 1858840..1859124 (-)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A0P9IXK3
• Locus tag: KIJ28_RS08285
• Protein ID: WP_004418474.1
• Coordinates: 1859114..1859353 (-)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KIJ28_RS08265 (KIJ28_08265)	1854982..1856910	+	1929	WP_016567635.1	methyl-accepting chemotaxis protein	-
KIJ28_RS08270 (KIJ28_08270)	1856944..1857876	-	933	WP_032660393.1	DMT family transporter	-
KIJ28_RS08275 (KIJ28_08275)	1857951..1858805	+	855	WP_003423353.1	LysR family transcriptional regulator	-
KIJ28_RS08280 (KIJ28_08280)	1858840..1859124	-	285	WP_103363385.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
KIJ28_RS08285 (KIJ28_08285)	1859114..1859353	-	240	WP_004418474.1	CopG family ribbon-helix-helix protein	Antitoxin
KIJ28_RS08290 (KIJ28_08290)	1859513..1860529	-	1017	WP_003423368.1	1-aminocyclopropane-1-carboxylate deaminase	-
KIJ28_RS08295 (KIJ28_08295)	1860716..1861222	+	507	WP_003315203.1	Lrp/AsnC family transcriptional regulator	-
KIJ28_RS08300 (KIJ28_08300)	1861371..1862279	+	909	WP_032660395.1	DUF808 domain-containing protein	-
KIJ28_RS08305 (KIJ28_08305)	1862456..1863241	-	786	WP_003396313.1	outer membrane protein OmpK	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-89)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-41)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10659.37 Da
• Isoelectric Point: 10.4249

>T202456 WP_103363385.1 NZ_CP074578:c1859124-1858840 [Pseudomonas syringae]
MQVEWLKTALKNLDEEAAYIALDNPAAAAAFVKAIQSNVTQLASFPAMGREGRIAGTREWPLPDLPYLIPYRIRSGRLQV
LRIFHTRRQSPPVW

Nucleotide

• Length: 285 bp

>T202456 NZ_CP099399:c560418-559960 [Rhizobium sp. Pop5]
GTGATCGGATGGCTGCTCGACACGAATGTCATTGCAGCGCTGATCAATCCGAATGGCGCACCCTCCGTCAAATCCTGGGC
TGCCGCTCAGGATGAGGAGCAGATGTTCATCAGCGTCCTCACTCTGGCGGAATATGACAAAGGCATCGAAAATCTGCCTG
AAGACGACCAGAACCGCTATCGCTATATAGCTGCGCGCGATGCTCTGGAGGAGCGGTTCTCCCAGCGTATTCTCTCGTTG
AGCGACAAGGCCGTCAGGCATTGGGGTTCTGTTTCAGGGCGCGTAAAACTGCGAACCGGACACACGCCGCCGGTCATCGA
CACGATGTTGGCCGTCACTGCAATCGAGCACAATCTCTATTTGGCCACGCGGAATGTCAAGGATAAGCGCTTCTCCGGCG
CAGCAGTTTTCGATCCATGGACCAACGATCCGGATCAATTTCCGCTGCGCCGGAAATAA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 8670.76 Da
• Isoelectric Point: 4.4217

>AT202456 WP_004418474.1 NZ_CP074578:c1859353-1859114 [Pseudomonas syringae]
MSTMSLRLPDEMADTLAHLAKATGRSKSFLALDALREYLTREAWQIAEIQRAIEEADAGEFASPDDVKAVMDKWSGNAG

Nucleotide

• Length: 240 bp

>AT202456 NZ_CP099399:c560678-560415 [Rhizobium sp. Pop5]
ATGAGAAAAGTCATAGAGCAAAGCTGGAAGCTCGAGGACGCCAAGGCGCGCTTCAGCGAGGTGGTGCGCCGCGCCCGCAG
CGAAGGGCCACAACGGGTCACTGTTCGCGGCAAAGACAGCGTCGTGATCATCAGCGTCGAGGAGCTCGAGCAGTTGATCA
AGGCCGAACCGAAGAAGCCTTTGGTCGACTTCATGGAGAGCCTTGCCCTTAAGGAACTCGACATCGAACGGGAGAGAGAT
TACGGCCGGGATGTCGAGCTGTGA

Structures

Antitoxin

• AlphaFold DB: A0A0P9IXK3