202415

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ygfYX/Cpta(toxin)
Location 3135050..3135695 Replicon chromosome
Accession NZ_CP074572
Organism Shewanella dokdonensis strain DSM 23626

Toxin (Protein)


Gene name ygfX Uniprot ID -
Locus tag KHX94_RS15110 Protein ID WP_213681259.1
Coordinates 3135276..3135695 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name ygfY Uniprot ID -
Locus tag KHX94_RS15105 Protein ID WP_213683469.1
Coordinates 3135050..3135289 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KHX94_RS15080 (KHX94_15075) 3130757..3131583 + 827 Protein_3002 prolipoprotein diacylglyceryl transferase -
KHX94_RS15085 (KHX94_15080) 3131583..3132377 + 795 WP_213681256.1 thymidylate synthase -
KHX94_RS15090 (KHX94_15085) 3132497..3133672 + 1176 WP_213681257.1 Na+/H+ antiporter NhaA -
KHX94_RS15095 (KHX94_15090) 3133669..3134052 + 384 WP_213681258.1 hypothetical protein -
KHX94_RS15100 (KHX94_15095) 3134068..3134972 + 905 Protein_3006 transcriptional activator NhaR -
KHX94_RS15105 (KHX94_15100) 3135050..3135289 + 240 WP_213683469.1 succinate dehydrogenase assembly factor 2 Antitoxin
KHX94_RS15110 (KHX94_15105) 3135276..3135695 + 420 WP_213681259.1 hypothetical protein Toxin
KHX94_RS15115 (KHX94_15110) 3135683..3137293 - 1611 WP_213681260.1 L-aspartate oxidase -
KHX94_RS15120 (KHX94_15115) 3137496..3138074 + 579 WP_133038041.1 RNA polymerase sigma factor RpoE -
KHX94_RS15125 (KHX94_15120) 3138102..3138701 + 600 WP_213681261.1 RseA family anti-sigma factor -
KHX94_RS15130 (KHX94_15125) 3138711..3139643 + 933 WP_213681262.1 MucB/RseB C-terminal domain-containing protein -
KHX94_RS15135 (KHX94_15130) 3139654..3140145 + 492 WP_213681263.1 SoxR reducing system RseC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(4-133)

Antitoxin

Flavinator of succinate dehydrogenase

(4-75)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 16588.25 Da        Isoelectric Point: 8.6115

>T202415 WP_213681259.1 NZ_CP074572:3135276-3135695 [Shewanella dokdonensis]
VRHHSFTVTSSFGQYLALLVLAVICLLSFRFWPALDYRYYPFIRWGLFGVLACYFCYQLWRLRTWKIRFWLSDNGQGQFG
AEQMFTVGAPVLVTPWLVSFSCIQTDGFHRLYLFRDMFDDTDYRHLCRLLLHRDSPYSG

Download         Length: 420 bp

>T202415 NZ_CP099387:2417908-2418096 [Citrobacter braakii]
GTGAAGCAAAGTGAGTTCAGACGCTGGCTTGAATCTCAGGGAGTGGCTGTTACAAACGGCTCAAATCATCTGAAGTTGAG
GTACCAGGGAAGGCGTAGCGTTATGCCCAGGCATCCTGGTGATGAAATAAAAGAAGCCTTGCGAAAATCGATCCTGAAGC
AGCTTGGTTTACAGTCATCATCAATATGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9230.81 Da        Isoelectric Point: 5.7874

>AT202415 WP_213683469.1 NZ_CP074572:3135050-3135289 [Shewanella dokdonensis]
MNFARVKWACRRGMLELDVLFQLFVDKYYQDLSDTDKACFVRLLECEDPQLFAWFMGHEKCPDPLLADMVAKVRGRAAP

Download         Length: 240 bp

>AT202415 NZ_CP099387:2418128-2418544 [Citrobacter braakii]
ATGCGTTATCCCGTTAATCTAATCCCCGCCGTGGAAGGTGGATTCGTGGTTTCTTTCCCGGATATTCCTGAAGCATTAAC
CCAGGGCGAAACCCGTCATGGGGCTTTGCAGGCTGCGCAGTCTGCATTGGTGACCGCTTTTGAATTCTATTTCGACGATA
ACGAACCGATTCCTTTACCTTCGGCGGTTGGCGCTGAAGGTGACTATGTGGAAATCCCCCTGAGCATTGCGTCGAAGGTT
CTTTTGTTAAATGCCTTTCTTGAATCAAAAATCACCCAGCAGGAGCTGGCAAACAGGATCGGCAGGCCTAAGCAGGAAAT
TACCCGTTTGTTCGATTTAAAGCACGCGACAAAAATTGATGCTGTGCAAATAGCTGCACGCGCCTTAGGCAAGGAGCTGT
CAGTAACAATGTTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References