202414

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 2963923..2964433 Replicon chromosome
Accession NZ_CP074572
Organism Shewanella dokdonensis strain DSM 23626

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag KHX94_RS14215 Protein ID WP_213681149.1
Coordinates 2964170..2964433 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag KHX94_RS14210 Protein ID WP_213681148.1
Coordinates 2963923..2964177 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KHX94_RS14195 (KHX94_14190) 2959786..2960451 - 666 WP_213681145.1 lamin tail domain-containing protein -
KHX94_RS14200 (KHX94_14195) 2960837..2962525 - 1689 WP_213681146.1 NAD-dependent malic enzyme -
KHX94_RS14205 (KHX94_14200) 2963063..2963446 + 384 WP_213681147.1 hypothetical protein -
KHX94_RS14210 (KHX94_14205) 2963923..2964177 + 255 WP_213681148.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
KHX94_RS14215 (KHX94_14210) 2964170..2964433 + 264 WP_213681149.1 Txe/YoeB family addiction module toxin Toxin
KHX94_RS14220 (KHX94_14215) 2964779..2965405 + 627 WP_213681150.1 rhomboid family intramembrane serine protease -
KHX94_RS14225 (KHX94_14220) 2965876..2966375 - 500 Protein_2846 DUF4447 family protein -
KHX94_RS14230 (KHX94_14225) 2966420..2966824 - 405 WP_213681151.1 SMI1/KNR4 family protein -
KHX94_RS14235 (KHX94_14230) 2966959..2969058 - 2100 WP_213681152.1 M13-type metalloendopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10406.83 Da        Isoelectric Point: 9.3929

>T202414 WP_213681149.1 NZ_CP074572:2964170-2964433 [Shewanella dokdonensis]
MNSRLLSWTDEAWNDYEYWQPQDKKTLKRINKLITNVKRAPFEGIGKPEALKENLAGFWSRRIDDKNRLVYAVDDQAITI
LSCRYHY

Download         Length: 264 bp

>T202414 NZ_CP099387:824228-824635 [Citrobacter braakii]
GTGGTCCAGTGGCAATCTGATTTACGCGTTTCATGGCGCGCGCAATGGCTTTCGTTGCTCATTCATGGGCTGGTCGCGGT
ATTTATTTTATTGATGCCCTGGCCATTGAGCTACACCCCATTATGGCTGGTTCTGCTCTCTCTGGTGGTGTTCGATAGCG
TCCGTAGCCAGCGCCGAATCAATGCCTGTCAGGGCGAGATTCGGCTGTTGATGGACGGTCGTCTGCGCTGGCAAGGGCAA
GAGTGGACTATTGCTAGCGCACCCTGGATGATCAAAACAGGCATGATGCTGCGTTTACGTTCCGATGCCGGAAAACGTCA
GCATTTGTGGCTGGCGGCAGACAGTATGGATGACGCGGAGTGGCGGGATTTGCGGCGGTTAATACTGCAACAGGCGAGGC
AGGGATAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9454.63 Da        Isoelectric Point: 4.7335

>AT202414 WP_213681148.1 NZ_CP074572:2963923-2964177 [Shewanella dokdonensis]
MRIVSFTEARNSLKSVLDGVVNDVDTTVITRRDAEDAVVMSLDYYNSLMETVHLLRSPANAEHLNRSIAQYKAGQTTLRD
LIDE

Download         Length: 255 bp

>AT202414 NZ_CP099387:823981-824247 [Citrobacter braakii]
ATGGATATTAACAACAAAGCACGTATTCATTGGGCATGCCGTCGCGGTATGCGTGAGCTGGACATCTCGATCATGCCGTT
TTTCGAACATGAATATGACAGCTTAAGTGACGAAGAAAAACGTATCTTTATCCGTCTGCTAGAATGTGATGATCCAGACT
TATTTAACTGGTTGATGAATCATGGGAAACCGGCTGATGCTCAGCTAGAGCAGATGGTGCGACTTATCCAGACACGGAAT
CGGGAACGTGGTCCAGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References