Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 3381061..3381590 Replicon chromosome
Accession NZ_CP074570
Organism Paraneptunicella aestuarii strain NBU2194

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag KIH87_RS12855 Protein ID WP_232358270.1
Coordinates 3381297..3381590 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag KIH87_RS12850 Protein ID WP_232358269.1
Coordinates 3381061..3381297 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KIH87_RS12820 (KIH87_12870) 3376257..3377321 - 1065 WP_232358263.1 EscU/YscU/HrcU family type III secretion system export apparatus switch protein -
KIH87_RS12825 (KIH87_12875) 3377321..3378097 - 777 WP_232358264.1 flagellar biosynthetic protein FliR -
KIH87_RS12830 (KIH87_12880) 3378099..3378362 - 264 WP_232358265.1 flagellar biosynthetic protein FliQ -
KIH87_RS12835 (KIH87_12885) 3378400..3379524 - 1125 WP_232358266.1 hypothetical protein -
KIH87_RS12840 (KIH87_12890) 3380023..3380499 + 477 WP_232358267.1 hypothetical protein -
KIH87_RS12845 (KIH87_12895) 3380512..3381018 - 507 WP_232358268.1 hemagglutinin repeat-containing protein -
KIH87_RS12850 (KIH87_12900) 3381061..3381297 + 237 WP_232358269.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
KIH87_RS12855 (KIH87_12905) 3381297..3381590 + 294 WP_232358270.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KIH87_RS12860 (KIH87_12910) 3381733..3382194 + 462 WP_232358271.1 hypothetical protein -
KIH87_RS12865 (KIH87_12915) 3382360..3382599 + 240 WP_232358272.1 integrase core domain-containing protein -
KIH87_RS12870 (KIH87_12920) 3382938..3383285 - 348 WP_232358273.1 hypothetical protein -
KIH87_RS12875 (KIH87_12925) 3383290..3383652 - 363 WP_232358274.1 papain-like cysteine protease family protein -
KIH87_RS12880 (KIH87_12930) 3383754..3384164 - 411 WP_232358275.1 hypothetical protein -
KIH87_RS12885 (KIH87_12935) 3384523..3385041 - 519 WP_232358276.1 hypothetical protein -
KIH87_RS19435 (KIH87_12940) 3385052..3385657 - 606 WP_269751475.1 hypothetical protein -
KIH87_RS12895 (KIH87_12945) 3385810..3386061 - 252 WP_232358277.1 MafI family immunity protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Antitoxin ParD

(1-73)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11243.86 Da        Isoelectric Point: 9.3067

>T202406 WP_232358270.1 NZ_CP074570:3381297-3381590 [Paraneptunicella aestuarii]
VTTYLLSPAAQASLKNIKAYSLENFGTIQTRHYLKSLRERMQALAENPERGRIRDELKVGFYSDFIGSHTIYYRIKPPHI
EIIDVLHQSMDPSKHVE

Download         Length: 294 bp

>T202406 NZ_CP099386:799303-799710 [Citrobacter braakii]
GTGGTCCAGTGGCAATCTGATTTACGCGTTTCATGGCGCGCGCAATGGCTTTCGTTGCTCATTCATGGGCTGGTCGCGGT
ATTTATTTTATTGATGCCCTGGCCATTGAGCTACACCCCATTATGGCTGGTTCTGCTCTCTCTGGTGGTGTTCGATAGCG
TCCGTAGCCAGCGCCGAATCAATGCCTGTCAGGGCGAGATTCGGCTGTTGATGGACGGTCGTCTGCGCTGGCAAGGGCAA
GAGTGGACTATTGCTAGCGCACCCTGGATGATCAAAACAGGCATGATGCTGCGTTTACGTTCCGATGCTGGAAAACGTCA
GCATTTGTGGCTGGCGGCAGACAGTATGGATGACGCGGAGTGGCGGGATTTACGGCGGTTAATACTGCAACAGGCGAGGC
AGGGATAA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8910.07 Da        Isoelectric Point: 4.6536

>AT202406 WP_232358269.1 NZ_CP074570:3381061-3381297 [Paraneptunicella aestuarii]
MQRNTSVTLGEHFGQFIEQKVQQGRFESTSEAVRAGLRLLEEQEMKLDILRKKLEVGETQLDRGEGIDGDKFMQDLIG

Download         Length: 237 bp

>AT202406 NZ_CP099386:799056-799322 [Citrobacter braakii]
ATGGATATTAACAACAAAGCACGTATTCATTGGGCATGCCGTCGCGGTATGCGTGAGCTGGACATCTCGATCATGCCGTT
TTTCGAACATGAATATGACAGCTTAAGTGACGAAGAAAAACGTATCTTTATCCGTCTGCTAGAATGTGATGATCCAGACT
TATTTAACTGGTTGATGAATCATGGGAAACCGGCTGATGCTCAGCTAGAGCAGATGGTGCGACTTATCCAGACACGGAAT
CGGGAACGTGGTCCAGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References