Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 3009761..3010304 Replicon chromosome
Accession NZ_CP074570
Organism Paraneptunicella aestuarii strain NBU2194

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KIH87_RS11745 Protein ID WP_232358055.1
Coordinates 3010032..3010304 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KIH87_RS11740 Protein ID WP_232358054.1
Coordinates 3009761..3010039 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KIH87_RS11710 (KIH87_11755) 3004871..3005437 - 567 WP_232358048.1 helix-turn-helix domain-containing protein -
KIH87_RS11715 (KIH87_11760) 3005644..3005874 + 231 WP_232358049.1 helix-turn-helix transcriptional regulator -
KIH87_RS11720 (KIH87_11765) 3006368..3006856 - 489 WP_232358050.1 helix-turn-helix domain-containing protein -
KIH87_RS11725 (KIH87_11770) 3007027..3007314 + 288 WP_232358051.1 helix-turn-helix transcriptional regulator -
KIH87_RS11730 (KIH87_11775) 3007345..3007644 + 300 WP_232358052.1 hypothetical protein -
KIH87_RS11735 (KIH87_11780) 3007730..3009454 - 1725 WP_232358053.1 hypothetical protein -
KIH87_RS11740 (KIH87_11785) 3009761..3010039 + 279 WP_232358054.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
KIH87_RS11745 (KIH87_11790) 3010032..3010304 + 273 WP_232358055.1 type II toxin-antitoxin system YafQ family toxin Toxin
KIH87_RS11750 (KIH87_11795) 3012301..3014091 - 1791 WP_232358056.1 reverse transcriptase/maturase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(3-82)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10391.09 Da        Isoelectric Point: 9.4325

>T202405 WP_232358055.1 NZ_CP074570:3010032-3010304 [Paraneptunicella aestuarii]
MLNLEYSSQFKKDFKKITKLPIADIVEVGHVIKQLQLGNPLAEKYVDHALSGNWQHYRDCHIKPDLVLIYKAETSTLKLA
RIGSHSELFR

Download         Length: 273 bp

>T202405 NZ_CP099386:43316-43657 [Citrobacter braakii]
ATGTGGGAAGTGGAAACAACGGATGTTTTCGATAAATGGTTTGACGTACAGACCGAGGCGCTCAAGGAAGATATGCTCGC
AGCGATGATGATTTTATCCGAGTATGGTCCTCAGTTAGGCAGGCCGTTTGCTGATACGGTAAATGCTTCTGCTTTTTCAA
ATATGAAAGAGTTGCGAGTGCAGCATCAGGGCAACCCGATTCGGGCGTTCTTCGTGTTTGATCCTTCTCGCCATGGCATC
GTGTTATGCGCTGGCGACAAAACAGGGTTAAACGAGAAGAAATTCTATAAAGAGATGATCAGGCTTGCTGACGCTGAGTA
CCGAAATCACCTTAATAAGTAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 9964.43 Da        Isoelectric Point: 4.8004

>AT202405 WP_232358054.1 NZ_CP074570:3009761-3010039 [Paraneptunicella aestuarii]
MKTEMLSTRIDPETKIAFTNVCEEMGLSPSQAIKLFAKAVINYGGIPFELKAKQPNAITASAIQELESGKGNKAKDVDEL
FETMGISQGRDA

Download         Length: 279 bp

>AT202405 NZ_CP099386:43666-43965 [Citrobacter braakii]
ATGGCGACGCTTAAAGAATTGATGGCGAAACAAAGCCCGGAAAGCCAAGAGCGCATTGCTGAAAAAGTAGAAGTGCTACG
TCAGGTGATTGCGTTAAATATGTTACGGGAAGAACTGAATCTCTCTCAGGCGGAACTTGCCTCGGCAATGGGCGTTAAGC
AGCCAACAATCGCAAAAATGGAACAGGCGGATAACGATCCTCGTCTGTCGACGCTTAAGCGTTATGTCACAGCGTTAGGT
GGCGAACTGAGCATTGATGTTAAGTTACCTACAGGTAAAAGAGTCGCGTTTCATCTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References